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Enhanced Solubility and Biological Activity of Dexibuprofen-Loaded Silica-Based Ternary Solid Dispersions

The current study was designed to formulate ternary solid dispersions (TSDs) of dexibuprofen (Dex) by solvent evaporation to augment the solubility and dissolution profile, in turn providing gastric protection and effective anti-inflammatory activity. Initially, nine formulations (S1 to S9) of binar...

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Detalles Bibliográficos
Autores principales: Asim, Muhammad, Nazir, Marriam, Chauhdary, Zunera, Irfan, Muhammad, Khalid, Syed Haroon, Asghar, Sajid, Usra, Felimban, Raed I., Majrashi, Mohammed A, Hazzazi, Mohannad S., Alissa, Mohammed, Qahl, Safa H, Hussain, Ghulam, Rasul, Azhar, Chatha, Shahzad Ali Shahid, Khan, Ikram Ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958995/
https://www.ncbi.nlm.nih.gov/pubmed/36839721
http://dx.doi.org/10.3390/pharmaceutics15020399