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Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes

In this study, we aimed to map and characterize the choroidal thickness over a wide area from the posterior pole to the vortex vein in normal eyes. This observational study included 146 healthy eyes (63 male). Three-dimensional volume data were acquired to create a choroidal thickness map using swep...

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Autores principales: Mihara, Naohisa, Sonoda, Shozo, Terasaki, Hiroto, Shiihara, Hideki, Sakono, Takato, Funatsu, Ryoh, Sakamoto, Taiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959021/
https://www.ncbi.nlm.nih.gov/pubmed/36836042
http://dx.doi.org/10.3390/jcm12041505
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author Mihara, Naohisa
Sonoda, Shozo
Terasaki, Hiroto
Shiihara, Hideki
Sakono, Takato
Funatsu, Ryoh
Sakamoto, Taiji
author_facet Mihara, Naohisa
Sonoda, Shozo
Terasaki, Hiroto
Shiihara, Hideki
Sakono, Takato
Funatsu, Ryoh
Sakamoto, Taiji
author_sort Mihara, Naohisa
collection PubMed
description In this study, we aimed to map and characterize the choroidal thickness over a wide area from the posterior pole to the vortex vein in normal eyes. This observational study included 146 healthy eyes (63 male). Three-dimensional volume data were acquired to create a choroidal thickness map using swept-source optical coherence tomography. The map was classified as type A if an area with a choroidal thickness >250 µm in the vertical direction from the optic disc, and the area corresponding to the watershed was not observed, or as type B if such an area was observed. The relationship between the ratio of groups A to B and age was compared by classifying the age for three age groups: <40, 40–60, and >60 years in men and women. In men and women, 69.8% and 49.4% were classified as type A, respectively, with significant sex differences (p = 0.013). The proportion of type B decreased with increasing age in both the sexes. There was a significant difference between ≤60 and >60 years in men and between ≤40 and >40 years in women (p < 0.05). To conclude, the wide-area choroidal thickness and the age-dependent changes in healthy eyes differed between the sexes.
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spelling pubmed-99590212023-02-26 Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes Mihara, Naohisa Sonoda, Shozo Terasaki, Hiroto Shiihara, Hideki Sakono, Takato Funatsu, Ryoh Sakamoto, Taiji J Clin Med Article In this study, we aimed to map and characterize the choroidal thickness over a wide area from the posterior pole to the vortex vein in normal eyes. This observational study included 146 healthy eyes (63 male). Three-dimensional volume data were acquired to create a choroidal thickness map using swept-source optical coherence tomography. The map was classified as type A if an area with a choroidal thickness >250 µm in the vertical direction from the optic disc, and the area corresponding to the watershed was not observed, or as type B if such an area was observed. The relationship between the ratio of groups A to B and age was compared by classifying the age for three age groups: <40, 40–60, and >60 years in men and women. In men and women, 69.8% and 49.4% were classified as type A, respectively, with significant sex differences (p = 0.013). The proportion of type B decreased with increasing age in both the sexes. There was a significant difference between ≤60 and >60 years in men and between ≤40 and >40 years in women (p < 0.05). To conclude, the wide-area choroidal thickness and the age-dependent changes in healthy eyes differed between the sexes. MDPI 2023-02-14 /pmc/articles/PMC9959021/ /pubmed/36836042 http://dx.doi.org/10.3390/jcm12041505 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mihara, Naohisa
Sonoda, Shozo
Terasaki, Hiroto
Shiihara, Hideki
Sakono, Takato
Funatsu, Ryoh
Sakamoto, Taiji
Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes
title Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes
title_full Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes
title_fullStr Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes
title_full_unstemmed Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes
title_short Sex- and Age-Dependent Wide-Field Choroidal Thickness Differences in Healthy Eyes
title_sort sex- and age-dependent wide-field choroidal thickness differences in healthy eyes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959021/
https://www.ncbi.nlm.nih.gov/pubmed/36836042
http://dx.doi.org/10.3390/jcm12041505
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