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COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil

The impact of coronavirus disease 2019 (COVID-19) on people living with human T-cell leukemia virus type 1 (HTLV-1) is unknown. The aim of this study is to evaluate the COVID-19 risk factors and outcomes of HTLV-1-infected individuals. A retrospective study of seropositive HTLV-1 outpatients seen du...

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Autores principales: Puccioni-Sohler, Marzia, Miranda, Alana Cristina Jasset, da Silva Mello, Cíntia, Magalhães, Stéphanie Monnerat, dos Santos Rodrigues, Luciane Cardoso, Signorini, Dario J. H. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959153/
https://www.ncbi.nlm.nih.gov/pubmed/36839514
http://dx.doi.org/10.3390/pathogens12020242
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author Puccioni-Sohler, Marzia
Miranda, Alana Cristina Jasset
da Silva Mello, Cíntia
Magalhães, Stéphanie Monnerat
dos Santos Rodrigues, Luciane Cardoso
Signorini, Dario J. H. P.
author_facet Puccioni-Sohler, Marzia
Miranda, Alana Cristina Jasset
da Silva Mello, Cíntia
Magalhães, Stéphanie Monnerat
dos Santos Rodrigues, Luciane Cardoso
Signorini, Dario J. H. P.
author_sort Puccioni-Sohler, Marzia
collection PubMed
description The impact of coronavirus disease 2019 (COVID-19) on people living with human T-cell leukemia virus type 1 (HTLV-1) is unknown. The aim of this study is to evaluate the COVID-19 risk factors and outcomes of HTLV-1-infected individuals. A retrospective study of seropositive HTLV-1 outpatients seen during the COVID-19 pandemic period (2020–2022) was conducted in a Tertiary Hospital in Rio de Janeiro, Brazil. We compared the demographic and comorbidity/risk factors in patients with COVID-19 and non-COVID-19 diagnoses. In addition, the clinical features of COVID-19 and vaccination status were also investigated in 51 HTLV-1-infected individuals. The majority (88.2%) had COVID-19 comorbidity/risk factors. Seven cases were vaccinated against COVID-19. Overall, 19 out of 51 (37.3%) individuals were diagnosed with COVID-19. We found differences only in the frequency of anxiety in both groups: 57.9% in the COVID-19 group vs. 15.6% in the non-COVID-19 (p < 0.05) group. Thirteen out of nineteen (68%) of the COVID-19 cases progressed to mild/moderate illness, one remained asymptomatic, and 26.3% progressed to severe illness. All of the individuals recovered at home, but the majority (57.9%) developed post-COVID-19 symptoms: anosmia and ageusia (31.6%), worsening anxiety (15.8%), and a feeling of pain in the legs (15.8%). The patients with post-COVID-19 conditions were unvaccinated. Our findings show that HTLV-1 did not increase the risk of lethal COVID-19 and underline the importance of promoting mental health in HTLV-1-infected individuals.
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spelling pubmed-99591532023-02-26 COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil Puccioni-Sohler, Marzia Miranda, Alana Cristina Jasset da Silva Mello, Cíntia Magalhães, Stéphanie Monnerat dos Santos Rodrigues, Luciane Cardoso Signorini, Dario J. H. P. Pathogens Article The impact of coronavirus disease 2019 (COVID-19) on people living with human T-cell leukemia virus type 1 (HTLV-1) is unknown. The aim of this study is to evaluate the COVID-19 risk factors and outcomes of HTLV-1-infected individuals. A retrospective study of seropositive HTLV-1 outpatients seen during the COVID-19 pandemic period (2020–2022) was conducted in a Tertiary Hospital in Rio de Janeiro, Brazil. We compared the demographic and comorbidity/risk factors in patients with COVID-19 and non-COVID-19 diagnoses. In addition, the clinical features of COVID-19 and vaccination status were also investigated in 51 HTLV-1-infected individuals. The majority (88.2%) had COVID-19 comorbidity/risk factors. Seven cases were vaccinated against COVID-19. Overall, 19 out of 51 (37.3%) individuals were diagnosed with COVID-19. We found differences only in the frequency of anxiety in both groups: 57.9% in the COVID-19 group vs. 15.6% in the non-COVID-19 (p < 0.05) group. Thirteen out of nineteen (68%) of the COVID-19 cases progressed to mild/moderate illness, one remained asymptomatic, and 26.3% progressed to severe illness. All of the individuals recovered at home, but the majority (57.9%) developed post-COVID-19 symptoms: anosmia and ageusia (31.6%), worsening anxiety (15.8%), and a feeling of pain in the legs (15.8%). The patients with post-COVID-19 conditions were unvaccinated. Our findings show that HTLV-1 did not increase the risk of lethal COVID-19 and underline the importance of promoting mental health in HTLV-1-infected individuals. MDPI 2023-02-03 /pmc/articles/PMC9959153/ /pubmed/36839514 http://dx.doi.org/10.3390/pathogens12020242 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Puccioni-Sohler, Marzia
Miranda, Alana Cristina Jasset
da Silva Mello, Cíntia
Magalhães, Stéphanie Monnerat
dos Santos Rodrigues, Luciane Cardoso
Signorini, Dario J. H. P.
COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil
title COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil
title_full COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil
title_fullStr COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil
title_full_unstemmed COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil
title_short COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil
title_sort covid-19 among people living with htlv-1 infection in rio de janeiro, brazil
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959153/
https://www.ncbi.nlm.nih.gov/pubmed/36839514
http://dx.doi.org/10.3390/pathogens12020242
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