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COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil
The impact of coronavirus disease 2019 (COVID-19) on people living with human T-cell leukemia virus type 1 (HTLV-1) is unknown. The aim of this study is to evaluate the COVID-19 risk factors and outcomes of HTLV-1-infected individuals. A retrospective study of seropositive HTLV-1 outpatients seen du...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959153/ https://www.ncbi.nlm.nih.gov/pubmed/36839514 http://dx.doi.org/10.3390/pathogens12020242 |
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author | Puccioni-Sohler, Marzia Miranda, Alana Cristina Jasset da Silva Mello, Cíntia Magalhães, Stéphanie Monnerat dos Santos Rodrigues, Luciane Cardoso Signorini, Dario J. H. P. |
author_facet | Puccioni-Sohler, Marzia Miranda, Alana Cristina Jasset da Silva Mello, Cíntia Magalhães, Stéphanie Monnerat dos Santos Rodrigues, Luciane Cardoso Signorini, Dario J. H. P. |
author_sort | Puccioni-Sohler, Marzia |
collection | PubMed |
description | The impact of coronavirus disease 2019 (COVID-19) on people living with human T-cell leukemia virus type 1 (HTLV-1) is unknown. The aim of this study is to evaluate the COVID-19 risk factors and outcomes of HTLV-1-infected individuals. A retrospective study of seropositive HTLV-1 outpatients seen during the COVID-19 pandemic period (2020–2022) was conducted in a Tertiary Hospital in Rio de Janeiro, Brazil. We compared the demographic and comorbidity/risk factors in patients with COVID-19 and non-COVID-19 diagnoses. In addition, the clinical features of COVID-19 and vaccination status were also investigated in 51 HTLV-1-infected individuals. The majority (88.2%) had COVID-19 comorbidity/risk factors. Seven cases were vaccinated against COVID-19. Overall, 19 out of 51 (37.3%) individuals were diagnosed with COVID-19. We found differences only in the frequency of anxiety in both groups: 57.9% in the COVID-19 group vs. 15.6% in the non-COVID-19 (p < 0.05) group. Thirteen out of nineteen (68%) of the COVID-19 cases progressed to mild/moderate illness, one remained asymptomatic, and 26.3% progressed to severe illness. All of the individuals recovered at home, but the majority (57.9%) developed post-COVID-19 symptoms: anosmia and ageusia (31.6%), worsening anxiety (15.8%), and a feeling of pain in the legs (15.8%). The patients with post-COVID-19 conditions were unvaccinated. Our findings show that HTLV-1 did not increase the risk of lethal COVID-19 and underline the importance of promoting mental health in HTLV-1-infected individuals. |
format | Online Article Text |
id | pubmed-9959153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99591532023-02-26 COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil Puccioni-Sohler, Marzia Miranda, Alana Cristina Jasset da Silva Mello, Cíntia Magalhães, Stéphanie Monnerat dos Santos Rodrigues, Luciane Cardoso Signorini, Dario J. H. P. Pathogens Article The impact of coronavirus disease 2019 (COVID-19) on people living with human T-cell leukemia virus type 1 (HTLV-1) is unknown. The aim of this study is to evaluate the COVID-19 risk factors and outcomes of HTLV-1-infected individuals. A retrospective study of seropositive HTLV-1 outpatients seen during the COVID-19 pandemic period (2020–2022) was conducted in a Tertiary Hospital in Rio de Janeiro, Brazil. We compared the demographic and comorbidity/risk factors in patients with COVID-19 and non-COVID-19 diagnoses. In addition, the clinical features of COVID-19 and vaccination status were also investigated in 51 HTLV-1-infected individuals. The majority (88.2%) had COVID-19 comorbidity/risk factors. Seven cases were vaccinated against COVID-19. Overall, 19 out of 51 (37.3%) individuals were diagnosed with COVID-19. We found differences only in the frequency of anxiety in both groups: 57.9% in the COVID-19 group vs. 15.6% in the non-COVID-19 (p < 0.05) group. Thirteen out of nineteen (68%) of the COVID-19 cases progressed to mild/moderate illness, one remained asymptomatic, and 26.3% progressed to severe illness. All of the individuals recovered at home, but the majority (57.9%) developed post-COVID-19 symptoms: anosmia and ageusia (31.6%), worsening anxiety (15.8%), and a feeling of pain in the legs (15.8%). The patients with post-COVID-19 conditions were unvaccinated. Our findings show that HTLV-1 did not increase the risk of lethal COVID-19 and underline the importance of promoting mental health in HTLV-1-infected individuals. MDPI 2023-02-03 /pmc/articles/PMC9959153/ /pubmed/36839514 http://dx.doi.org/10.3390/pathogens12020242 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Puccioni-Sohler, Marzia Miranda, Alana Cristina Jasset da Silva Mello, Cíntia Magalhães, Stéphanie Monnerat dos Santos Rodrigues, Luciane Cardoso Signorini, Dario J. H. P. COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil |
title | COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil |
title_full | COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil |
title_fullStr | COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil |
title_full_unstemmed | COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil |
title_short | COVID-19 among People Living with HTLV-1 Infection in Rio de Janeiro, Brazil |
title_sort | covid-19 among people living with htlv-1 infection in rio de janeiro, brazil |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959153/ https://www.ncbi.nlm.nih.gov/pubmed/36839514 http://dx.doi.org/10.3390/pathogens12020242 |
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