Genetic Variation in CYP2D6 and SLC22A1 Affects Amlodipine Pharmacokinetics and Safety

Amlodipine is an antihypertensive drug with unknown pharmacogenetic biomarkers. This research is a candidate gene study that looked for associations between amlodipine pharmacokinetics and safety and pharmacogenes. Pharmacokinetic and safety data were taken from 160 volunteers from eight bioequivale...

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Detalles Bibliográficos
Autores principales: Soria-Chacartegui, Paula, Zubiaur, Pablo, Ochoa, Dolores, Villapalos-García, Gonzalo, Román, Manuel, Matas, Miriam, Figueiredo-Tor, Laura, Mejía-Abril, Gina, Calleja, Sofía, de Miguel, Alejandro, Navares-Gómez, Marcos, Martín-Vilchez, Samuel, Abad-Santos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959242/
https://www.ncbi.nlm.nih.gov/pubmed/36839726
http://dx.doi.org/10.3390/pharmaceutics15020404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959242/
https://www.ncbi.nlm.nih.gov/pubmed/36839726
http://dx.doi.org/10.3390/pharmaceutics15020404

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