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Genetic Variation in CYP2D6 and SLC22A1 Affects Amlodipine Pharmacokinetics and Safety
Amlodipine is an antihypertensive drug with unknown pharmacogenetic biomarkers. This research is a candidate gene study that looked for associations between amlodipine pharmacokinetics and safety and pharmacogenes. Pharmacokinetic and safety data were taken from 160 volunteers from eight bioequivale...
Autores principales: | Soria-Chacartegui, Paula, Zubiaur, Pablo, Ochoa, Dolores, Villapalos-García, Gonzalo, Román, Manuel, Matas, Miriam, Figueiredo-Tor, Laura, Mejía-Abril, Gina, Calleja, Sofía, de Miguel, Alejandro, Navares-Gómez, Marcos, Martín-Vilchez, Samuel, Abad-Santos, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959242/ https://www.ncbi.nlm.nih.gov/pubmed/36839726 http://dx.doi.org/10.3390/pharmaceutics15020404 |
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