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Targeting IKKβ Activity to Limit Sterile Inflammation in Acetaminophen-Induced Hepatotoxicity in Mice

The kinase activity of inhibitory κB kinase β (IKKβ) acts as a signal transducer in the activating pathway of nuclear factor-κB (NF-κB), a master regulator of inflammation and cell death in the development of numerous hepatocellular injuries. However, the importance of IKKβ activity on acetaminophen...

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Detalles Bibliográficos
Autores principales:	Kim, Song-Hee, Jung, Da-Eun, Song, Jin Yong, Jung, Jihye, Jung, Jae-Kyung, Lee, Heesoon, Roh, Eunmiri, Hong, Jin Tae, Han, Sang-Bae, Kim, Youngsoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959252/ https://www.ncbi.nlm.nih.gov/pubmed/36840032 http://dx.doi.org/10.3390/pharmaceutics15020710

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