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Discovery of Polyphenolic Natural Products as SARS-CoV-2 M(pro) Inhibitors for COVID-19

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has forced the development of direct-acting antiviral drugs due to the coronavirus disease 2019 (COVID-19) pandemic. The main protease of SARS-CoV-2 is a crucial enzyme that breaks down polyproteins synthesized from the viral RNA, maki...

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Detalles Bibliográficos
Autores principales: Krüger, Nadine, Kronenberger, Thales, Xie, Hang, Rocha, Cheila, Pöhlmann, Stefan, Su, Haixia, Xu, Yechun, Laufer, Stefan A., Pillaiyar, Thanigaimalai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959258/
https://www.ncbi.nlm.nih.gov/pubmed/37259339
http://dx.doi.org/10.3390/ph16020190