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Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife

Eastern roe deer (Capreolus pygargus) is a small ruminant and is widespread across China. This creature plays an important role in our ecological system. Although a few studies have been conducted to investigate pathogens harbored by this species, our knowledge of the virus diversity is still very s...

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Autores principales: Sun, Yue, Sun, Lanshun, Sun, Sheng, Tu, Zhongzhong, Liu, Yang, Yi, Le, Tu, Changchun, He, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959412/
https://www.ncbi.nlm.nih.gov/pubmed/36839428
http://dx.doi.org/10.3390/pathogens12020156
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author Sun, Yue
Sun, Lanshun
Sun, Sheng
Tu, Zhongzhong
Liu, Yang
Yi, Le
Tu, Changchun
He, Biao
author_facet Sun, Yue
Sun, Lanshun
Sun, Sheng
Tu, Zhongzhong
Liu, Yang
Yi, Le
Tu, Changchun
He, Biao
author_sort Sun, Yue
collection PubMed
description Eastern roe deer (Capreolus pygargus) is a small ruminant and is widespread across China. This creature plays an important role in our ecological system. Although a few studies have been conducted to investigate pathogens harbored by this species, our knowledge of the virus diversity is still very sparse. In this study, we conducted the whole virome profiling of a rescue-failed roe deer, which revealed a kobuvirus (KoV), a bocaparvovirus (BoV), and multiple circular single-stranded viruses. These viruses were mainly recovered from the rectum, but PCR detection showed systematic infection of the KoV. Particularly, the KoV and BoV exhibited closely genetic relationships with bovine and canine viruses, respectively, highly suggesting the spillover of viruses from domestic animals to wildlife. Although these viruses were unlikely to have been responsible for the death of the animal, they provide additional data to understand the virus spectrum harbored by roe deer. The transmission of viruses between domestic animals and wildlife highlights the need for extensive investigation of wildlife viruses.
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spelling pubmed-99594122023-02-26 Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife Sun, Yue Sun, Lanshun Sun, Sheng Tu, Zhongzhong Liu, Yang Yi, Le Tu, Changchun He, Biao Pathogens Communication Eastern roe deer (Capreolus pygargus) is a small ruminant and is widespread across China. This creature plays an important role in our ecological system. Although a few studies have been conducted to investigate pathogens harbored by this species, our knowledge of the virus diversity is still very sparse. In this study, we conducted the whole virome profiling of a rescue-failed roe deer, which revealed a kobuvirus (KoV), a bocaparvovirus (BoV), and multiple circular single-stranded viruses. These viruses were mainly recovered from the rectum, but PCR detection showed systematic infection of the KoV. Particularly, the KoV and BoV exhibited closely genetic relationships with bovine and canine viruses, respectively, highly suggesting the spillover of viruses from domestic animals to wildlife. Although these viruses were unlikely to have been responsible for the death of the animal, they provide additional data to understand the virus spectrum harbored by roe deer. The transmission of viruses between domestic animals and wildlife highlights the need for extensive investigation of wildlife viruses. MDPI 2023-01-18 /pmc/articles/PMC9959412/ /pubmed/36839428 http://dx.doi.org/10.3390/pathogens12020156 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Sun, Yue
Sun, Lanshun
Sun, Sheng
Tu, Zhongzhong
Liu, Yang
Yi, Le
Tu, Changchun
He, Biao
Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife
title Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife
title_full Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife
title_fullStr Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife
title_full_unstemmed Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife
title_short Virome Profiling of an Eastern Roe Deer Reveals Spillover of Viruses from Domestic Animals to Wildlife
title_sort virome profiling of an eastern roe deer reveals spillover of viruses from domestic animals to wildlife
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959412/
https://www.ncbi.nlm.nih.gov/pubmed/36839428
http://dx.doi.org/10.3390/pathogens12020156
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