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Development and Evaluation of a Novel One-Step RT-qPCR Targeting the Vero Gene for the Identification of False-Positive Results Caused by Inactivated Virus Vaccine Contamination

To identify false-positive SARS-CoV-2 test results caused by novel coronavirus inactivated vaccine contamination, a novel RT-qPCR targeting the ORF1ab and N genes of SARS-CoV-2 and Vero gene was developed. The amplification efficiency, precision, and lower limit of detection (LLOD) of the RT-qPCR as...

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Detalles Bibliográficos
Autores principales: Zheng, Xin-Qi, Yang, Wan-Bao, Xie, Lin, Wei, Zi-Han, Zhuang, Jiang-Xing, Yang, Tian-Ci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959469/
https://www.ncbi.nlm.nih.gov/pubmed/36851250
http://dx.doi.org/10.3390/vaccines11020372