AICAR Ameliorates Non-Alcoholic Fatty Liver Disease via Modulation of the HGF/NF-κB/SNARK Signaling Pathway and Restores Mitochondrial and Endoplasmic Reticular Impairments in High-Fat Diet-Fed Rats

Non-alcoholic fatty liver disease (NAFLD) is a global health problem characterized by altered lipid and redox homeostasis, mitochondrial dysfunction, and endoplasmic reticulum (ER) stress. The AMP-dependent kinase (AMPK) agonist 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) has been shown to...

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Detalles Bibliográficos
Autores principales: Zineldeen, Doaa Hussein, Tahoon, Nahid Mohamed, Sarhan, Naglaa Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959470/
https://www.ncbi.nlm.nih.gov/pubmed/36834782
http://dx.doi.org/10.3390/ijms24043367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959470/
https://www.ncbi.nlm.nih.gov/pubmed/36834782
http://dx.doi.org/10.3390/ijms24043367

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