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In Silico Computational Studies of Bioactive Secondary Metabolites from Wedelia trilobata against Anti-Apoptotic B-Cell Lymphoma-2 (Bcl-2) Protein Associated with Cancer Cell Survival and Resistance

In the present study, the binding affinity of 52 bioactive secondary metabolites from Wedelia trilobata towards the anti-apoptotic B-cell lymphoma-2 (Bcl-2) protein (PDB: 2W3L) structure was identified by using in silico molecular docking and molecular dynamics simulation. The molecular docking resu...

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Detalles Bibliográficos
Autores principales:	Gowtham, Hittanahallikoppal Gajendramurthy, Ahmed, Faiyaz, Anandan, Satish, Shivakumara, C. S., Bilagi, Ashween, Pradeep, Sushma, Shivamallu, Chandan, Shati, Ali A., Alfaifi, Mohammad Y., Elbehairi, Serag Eldin I., Achar, Raghu Ram, Silina, Ekaterina, Stupin, Victor, Murali, Mahadevamurthy, Kollur, Shiva Prasad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959492/ https://www.ncbi.nlm.nih.gov/pubmed/36838574 http://dx.doi.org/10.3390/molecules28041588

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