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Influence of the Drug Position on Bioactivity in Angiopep-2—Daunomycin Conjugates
The blood–brain barrier (BBB) is a semipermeable system, and, therefore, most of the active substances are poorly transported through this barrier, resulting in decreased therapeutic effects. Angiopep-2 (TFFYGGSRGKRNNFKTEEY) is a peptide ligand of low-density lipoprotein receptor-related protein-1 (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959518/ https://www.ncbi.nlm.nih.gov/pubmed/36834514 http://dx.doi.org/10.3390/ijms24043106 |