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Influence of the Drug Position on Bioactivity in Angiopep-2—Daunomycin Conjugates

The blood–brain barrier (BBB) is a semipermeable system, and, therefore, most of the active substances are poorly transported through this barrier, resulting in decreased therapeutic effects. Angiopep-2 (TFFYGGSRGKRNNFKTEEY) is a peptide ligand of low-density lipoprotein receptor-related protein-1 (...

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Detalles Bibliográficos
Autores principales:	Pethő, Lilla, Oláh-Szabó, Rita, Mező, Gábor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959518/ https://www.ncbi.nlm.nih.gov/pubmed/36834514 http://dx.doi.org/10.3390/ijms24043106

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