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Effect of Antihypertensive Drug (Chlorothiazide) on Fibrillation of Lysozyme: A Combined Spectroscopy, Microscopy, and Computational Study

Amyloid fibrils abnormally accumulate together in the human body under certain conditions, which can result in lethal conditions. Thus, blocking this aggregation may prevent or treat this disease. Chlorothiazide (CTZ) is a diuretic and is used to treat hypertension. Several previous studies suggest...

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Detalles Bibliográficos
Autores principales: Altwaijry, Nojood, Almutairi, Ghaliah S., Khan, Mohd Shahnawaz, Shaik, Gouse M., Alokail, Majed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959601/
https://www.ncbi.nlm.nih.gov/pubmed/36834523
http://dx.doi.org/10.3390/ijms24043112