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Transplantation of Adipose-Tissue-Engineered Constructs with CRISPR-Mediated UCP1 Activation
Thermogenic adipocytes have potential utility for the development of approaches to treat type 2 diabetes and obesity-associated diseases. Although several reports have proved the positive effect of beige and brown adipocyte transplantation in obese mice, translation to human cell therapy needs impro...
Autores principales: | Michurina, Svetlana, Stafeev, Iurii, Boldyreva, Maria, Truong, Vu Anh, Ratner, Elizaveta, Menshikov, Mikhail, Hu, Yu-Chen, Parfyonova, Yelena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959691/ https://www.ncbi.nlm.nih.gov/pubmed/36835254 http://dx.doi.org/10.3390/ijms24043844 |
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