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Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity

Cutaneous tuberculosis (CTB) is a very rare disease and accounts for only 1–2% of cases of extrapulmonary tuberculosis (EPTB). Due to the variety of its clinical manifestations, the uncharacteristic appearance of its lesions, resembling other dermatoses in the early stages, and the limited experienc...

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Autores principales: Kozińska, Monika, Augustynowicz-Kopeć, Ewa, Gamian, Andrzej, Chudzik, Anna, Paściak, Mariola, Zdziarski, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959720/
https://www.ncbi.nlm.nih.gov/pubmed/36839603
http://dx.doi.org/10.3390/pathogens12020331
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author Kozińska, Monika
Augustynowicz-Kopeć, Ewa
Gamian, Andrzej
Chudzik, Anna
Paściak, Mariola
Zdziarski, Przemysław
author_facet Kozińska, Monika
Augustynowicz-Kopeć, Ewa
Gamian, Andrzej
Chudzik, Anna
Paściak, Mariola
Zdziarski, Przemysław
author_sort Kozińska, Monika
collection PubMed
description Cutaneous tuberculosis (CTB) is a very rare disease and accounts for only 1–2% of cases of extrapulmonary tuberculosis (EPTB). Due to the variety of its clinical manifestations, the uncharacteristic appearance of its lesions, resembling other dermatoses in the early stages, and the limited experience of clinicians due to the rarity of CTB, diagnosis is very difficult. Particularly noteworthy is the fact that most cases of EPTB, including skin tuberculosis (TB), can be a manifestation of systemic involvement. In this paper, we present a case of an immunocompromised patient who was diagnosed with CTB almost a year after the first dermatological lesions were located on the lower extremities. At the same time, due to respiratory symptoms, a diagnosis of pulmonary TB (PTB) was made, and radiological and microbiological confirmations were obtained.
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spelling pubmed-99597202023-02-26 Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity Kozińska, Monika Augustynowicz-Kopeć, Ewa Gamian, Andrzej Chudzik, Anna Paściak, Mariola Zdziarski, Przemysław Pathogens Case Report Cutaneous tuberculosis (CTB) is a very rare disease and accounts for only 1–2% of cases of extrapulmonary tuberculosis (EPTB). Due to the variety of its clinical manifestations, the uncharacteristic appearance of its lesions, resembling other dermatoses in the early stages, and the limited experience of clinicians due to the rarity of CTB, diagnosis is very difficult. Particularly noteworthy is the fact that most cases of EPTB, including skin tuberculosis (TB), can be a manifestation of systemic involvement. In this paper, we present a case of an immunocompromised patient who was diagnosed with CTB almost a year after the first dermatological lesions were located on the lower extremities. At the same time, due to respiratory symptoms, a diagnosis of pulmonary TB (PTB) was made, and radiological and microbiological confirmations were obtained. MDPI 2023-02-15 /pmc/articles/PMC9959720/ /pubmed/36839603 http://dx.doi.org/10.3390/pathogens12020331 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Kozińska, Monika
Augustynowicz-Kopeć, Ewa
Gamian, Andrzej
Chudzik, Anna
Paściak, Mariola
Zdziarski, Przemysław
Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
title Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
title_full Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
title_fullStr Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
title_full_unstemmed Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
title_short Cutaneous and Pulmonary Tuberculosis—Diagnostic and Therapeutic Difficulties in a Patient with Autoimmunity
title_sort cutaneous and pulmonary tuberculosis—diagnostic and therapeutic difficulties in a patient with autoimmunity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959720/
https://www.ncbi.nlm.nih.gov/pubmed/36839603
http://dx.doi.org/10.3390/pathogens12020331
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