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The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy
Degenerative cervical myelopathy (DCM) consists of spinal cord damage due to its compression through the cervical spine. The leading cause is degenerative. The diagnosis is clinical, and the therapeutic approach is usually surgical. Confirmation of the diagnostic suspicion is done by magnetic resona...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959727/ https://www.ncbi.nlm.nih.gov/pubmed/36834385 http://dx.doi.org/10.3390/ijerph20043690 |
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author | Vázquez-Sánchez, Fernando Lloria-Gil, María del Carmen Gómez-Menéndez, Ana Isabel Isidro-Mesas, Francisco Echavarría-Íñiguez, Ana Martín-Alonso, Javier González-Bernal, Jerónimo González-Santos, Josefa Berardi, Anna Tofani, Marco Galeoto, Giovanni García-López, Beatriz |
author_facet | Vázquez-Sánchez, Fernando Lloria-Gil, María del Carmen Gómez-Menéndez, Ana Isabel Isidro-Mesas, Francisco Echavarría-Íñiguez, Ana Martín-Alonso, Javier González-Bernal, Jerónimo González-Santos, Josefa Berardi, Anna Tofani, Marco Galeoto, Giovanni García-López, Beatriz |
author_sort | Vázquez-Sánchez, Fernando |
collection | PubMed |
description | Degenerative cervical myelopathy (DCM) consists of spinal cord damage due to its compression through the cervical spine. The leading cause is degenerative. The diagnosis is clinical, and the therapeutic approach is usually surgical. Confirmation of the diagnostic suspicion is done by magnetic resonance imaging (MRI); however, this test lacks functional information of the spinal cord, the abnormality of which may precede involvement in neuroimaging. Neurophysiological examination using somatosensory evoked potentials (SSEPs) and transcranial magnetic stimulation (TMS) allows for an evaluation of spinal cord function, and provides information in the diagnostic process. Its role in the post-surgical follow-up of patients undergoing decompressive surgery is being studied. We present a retrospective study of 24 patients with DCM and surgical decompression who underwent neurophysiological tests (TMS and SSEP) before, 6, and 12 months after surgery. The result of the TMS and the SSEP in the post-operative follow-up did not correlate with the clinical outcome, either subjective or measured by clinical scales at six months. We only found post-surgical improvement of central conduction times (CMCTs) in patients with severe pre-surgical motor impairment on TMS. In patients with normal pre-surgical CMCT, we found a transient worsening with return to baseline at the one-year follow-up. Most patients presented pre-surgical increased P40 latency at diagnosis. CMCT and SSEP were more related to clinical outcomes one year after the surgical procedure and were very useful in diagnosing. |
format | Online Article Text |
id | pubmed-9959727 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99597272023-02-26 The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy Vázquez-Sánchez, Fernando Lloria-Gil, María del Carmen Gómez-Menéndez, Ana Isabel Isidro-Mesas, Francisco Echavarría-Íñiguez, Ana Martín-Alonso, Javier González-Bernal, Jerónimo González-Santos, Josefa Berardi, Anna Tofani, Marco Galeoto, Giovanni García-López, Beatriz Int J Environ Res Public Health Article Degenerative cervical myelopathy (DCM) consists of spinal cord damage due to its compression through the cervical spine. The leading cause is degenerative. The diagnosis is clinical, and the therapeutic approach is usually surgical. Confirmation of the diagnostic suspicion is done by magnetic resonance imaging (MRI); however, this test lacks functional information of the spinal cord, the abnormality of which may precede involvement in neuroimaging. Neurophysiological examination using somatosensory evoked potentials (SSEPs) and transcranial magnetic stimulation (TMS) allows for an evaluation of spinal cord function, and provides information in the diagnostic process. Its role in the post-surgical follow-up of patients undergoing decompressive surgery is being studied. We present a retrospective study of 24 patients with DCM and surgical decompression who underwent neurophysiological tests (TMS and SSEP) before, 6, and 12 months after surgery. The result of the TMS and the SSEP in the post-operative follow-up did not correlate with the clinical outcome, either subjective or measured by clinical scales at six months. We only found post-surgical improvement of central conduction times (CMCTs) in patients with severe pre-surgical motor impairment on TMS. In patients with normal pre-surgical CMCT, we found a transient worsening with return to baseline at the one-year follow-up. Most patients presented pre-surgical increased P40 latency at diagnosis. CMCT and SSEP were more related to clinical outcomes one year after the surgical procedure and were very useful in diagnosing. MDPI 2023-02-19 /pmc/articles/PMC9959727/ /pubmed/36834385 http://dx.doi.org/10.3390/ijerph20043690 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vázquez-Sánchez, Fernando Lloria-Gil, María del Carmen Gómez-Menéndez, Ana Isabel Isidro-Mesas, Francisco Echavarría-Íñiguez, Ana Martín-Alonso, Javier González-Bernal, Jerónimo González-Santos, Josefa Berardi, Anna Tofani, Marco Galeoto, Giovanni García-López, Beatriz The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy |
title | The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy |
title_full | The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy |
title_fullStr | The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy |
title_full_unstemmed | The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy |
title_short | The Role of Magnetic Transcranial Stimulation in the Diagnosis and Post-Surgical Follow-Up of Cervical Spondylotic Myelopathy |
title_sort | role of magnetic transcranial stimulation in the diagnosis and post-surgical follow-up of cervical spondylotic myelopathy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959727/ https://www.ncbi.nlm.nih.gov/pubmed/36834385 http://dx.doi.org/10.3390/ijerph20043690 |
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