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Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life

Objective: The objective of this study is to define the real-life clinical profile and therapeutic management of patients with idiopathic pulmonary fibrosis using artificial intelligence. Methods: We have conducted an observational, retrospective, non-interventional study using data from the Castill...

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Autores principales: Morena, Diego, Fernández, Jesús, Campos, Carolina, Castillo, María, López, Guillermo, Benavent, María, Izquierdo, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959732/
https://www.ncbi.nlm.nih.gov/pubmed/36836204
http://dx.doi.org/10.3390/jcm12041669
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author Morena, Diego
Fernández, Jesús
Campos, Carolina
Castillo, María
López, Guillermo
Benavent, María
Izquierdo, José Luis
author_facet Morena, Diego
Fernández, Jesús
Campos, Carolina
Castillo, María
López, Guillermo
Benavent, María
Izquierdo, José Luis
author_sort Morena, Diego
collection PubMed
description Objective: The objective of this study is to define the real-life clinical profile and therapeutic management of patients with idiopathic pulmonary fibrosis using artificial intelligence. Methods: We have conducted an observational, retrospective, non-interventional study using data from the Castilla-La Mancha Regional Healthcare Service (SESCAM) in Spain between January 2012 and December 2020. The Savana Manager 3.0 artificial intelligence platform was used to collect information from electronic medical records by applying natural language processing. Results: Our study includes 897 subjects whose diagnosis was compatible with idiopathic pulmonary fibrosis; 64.8% were men, with a mean age of 72.9 years (95% CI 71.9–73.8), and 35.2% were women, with a mean age of 76.8 years (95% CI 75.5–78). Patients who had a family history of IPF (98 patients; 12%) were younger and predominantly female (53.1%). Regarding treatment, 45% of patients received antifibrotic therapy. Patients who had undergone lung biopsy, chest CT, or bronchoscopy were younger than the patient population in whom these studies were not completed. Conclusions: This study has used artificial intelligence techniques to analyze a large population over a 9-year period and determine the situation of IPF in standard clinical practice by identifying the patient clinical profile, use of diagnostic tests and therapeutic management.
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spelling pubmed-99597322023-02-26 Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life Morena, Diego Fernández, Jesús Campos, Carolina Castillo, María López, Guillermo Benavent, María Izquierdo, José Luis J Clin Med Article Objective: The objective of this study is to define the real-life clinical profile and therapeutic management of patients with idiopathic pulmonary fibrosis using artificial intelligence. Methods: We have conducted an observational, retrospective, non-interventional study using data from the Castilla-La Mancha Regional Healthcare Service (SESCAM) in Spain between January 2012 and December 2020. The Savana Manager 3.0 artificial intelligence platform was used to collect information from electronic medical records by applying natural language processing. Results: Our study includes 897 subjects whose diagnosis was compatible with idiopathic pulmonary fibrosis; 64.8% were men, with a mean age of 72.9 years (95% CI 71.9–73.8), and 35.2% were women, with a mean age of 76.8 years (95% CI 75.5–78). Patients who had a family history of IPF (98 patients; 12%) were younger and predominantly female (53.1%). Regarding treatment, 45% of patients received antifibrotic therapy. Patients who had undergone lung biopsy, chest CT, or bronchoscopy were younger than the patient population in whom these studies were not completed. Conclusions: This study has used artificial intelligence techniques to analyze a large population over a 9-year period and determine the situation of IPF in standard clinical practice by identifying the patient clinical profile, use of diagnostic tests and therapeutic management. MDPI 2023-02-20 /pmc/articles/PMC9959732/ /pubmed/36836204 http://dx.doi.org/10.3390/jcm12041669 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Morena, Diego
Fernández, Jesús
Campos, Carolina
Castillo, María
López, Guillermo
Benavent, María
Izquierdo, José Luis
Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life
title Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life
title_full Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life
title_fullStr Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life
title_full_unstemmed Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life
title_short Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life
title_sort clinical profile of patients with idiopathic pulmonary fibrosis in real life
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959732/
https://www.ncbi.nlm.nih.gov/pubmed/36836204
http://dx.doi.org/10.3390/jcm12041669
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