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Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life
Objective: The objective of this study is to define the real-life clinical profile and therapeutic management of patients with idiopathic pulmonary fibrosis using artificial intelligence. Methods: We have conducted an observational, retrospective, non-interventional study using data from the Castill...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959732/ https://www.ncbi.nlm.nih.gov/pubmed/36836204 http://dx.doi.org/10.3390/jcm12041669 |
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author | Morena, Diego Fernández, Jesús Campos, Carolina Castillo, María López, Guillermo Benavent, María Izquierdo, José Luis |
author_facet | Morena, Diego Fernández, Jesús Campos, Carolina Castillo, María López, Guillermo Benavent, María Izquierdo, José Luis |
author_sort | Morena, Diego |
collection | PubMed |
description | Objective: The objective of this study is to define the real-life clinical profile and therapeutic management of patients with idiopathic pulmonary fibrosis using artificial intelligence. Methods: We have conducted an observational, retrospective, non-interventional study using data from the Castilla-La Mancha Regional Healthcare Service (SESCAM) in Spain between January 2012 and December 2020. The Savana Manager 3.0 artificial intelligence platform was used to collect information from electronic medical records by applying natural language processing. Results: Our study includes 897 subjects whose diagnosis was compatible with idiopathic pulmonary fibrosis; 64.8% were men, with a mean age of 72.9 years (95% CI 71.9–73.8), and 35.2% were women, with a mean age of 76.8 years (95% CI 75.5–78). Patients who had a family history of IPF (98 patients; 12%) were younger and predominantly female (53.1%). Regarding treatment, 45% of patients received antifibrotic therapy. Patients who had undergone lung biopsy, chest CT, or bronchoscopy were younger than the patient population in whom these studies were not completed. Conclusions: This study has used artificial intelligence techniques to analyze a large population over a 9-year period and determine the situation of IPF in standard clinical practice by identifying the patient clinical profile, use of diagnostic tests and therapeutic management. |
format | Online Article Text |
id | pubmed-9959732 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99597322023-02-26 Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life Morena, Diego Fernández, Jesús Campos, Carolina Castillo, María López, Guillermo Benavent, María Izquierdo, José Luis J Clin Med Article Objective: The objective of this study is to define the real-life clinical profile and therapeutic management of patients with idiopathic pulmonary fibrosis using artificial intelligence. Methods: We have conducted an observational, retrospective, non-interventional study using data from the Castilla-La Mancha Regional Healthcare Service (SESCAM) in Spain between January 2012 and December 2020. The Savana Manager 3.0 artificial intelligence platform was used to collect information from electronic medical records by applying natural language processing. Results: Our study includes 897 subjects whose diagnosis was compatible with idiopathic pulmonary fibrosis; 64.8% were men, with a mean age of 72.9 years (95% CI 71.9–73.8), and 35.2% were women, with a mean age of 76.8 years (95% CI 75.5–78). Patients who had a family history of IPF (98 patients; 12%) were younger and predominantly female (53.1%). Regarding treatment, 45% of patients received antifibrotic therapy. Patients who had undergone lung biopsy, chest CT, or bronchoscopy were younger than the patient population in whom these studies were not completed. Conclusions: This study has used artificial intelligence techniques to analyze a large population over a 9-year period and determine the situation of IPF in standard clinical practice by identifying the patient clinical profile, use of diagnostic tests and therapeutic management. MDPI 2023-02-20 /pmc/articles/PMC9959732/ /pubmed/36836204 http://dx.doi.org/10.3390/jcm12041669 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Morena, Diego Fernández, Jesús Campos, Carolina Castillo, María López, Guillermo Benavent, María Izquierdo, José Luis Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life |
title | Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life |
title_full | Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life |
title_fullStr | Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life |
title_full_unstemmed | Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life |
title_short | Clinical Profile of Patients with Idiopathic Pulmonary Fibrosis in Real Life |
title_sort | clinical profile of patients with idiopathic pulmonary fibrosis in real life |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959732/ https://www.ncbi.nlm.nih.gov/pubmed/36836204 http://dx.doi.org/10.3390/jcm12041669 |
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