Ball-Milling Preparation of the Drug–Drug Solid Form of Pioglitazone-Rosuvastatin at Different Molar Ratios: Characterization and Intrinsic Dissolution Rates Evaluation

Ball-milling using neat grinding (NG) or liquid-assisted grinding (LAG) by varying the polarity of the solvents allowed access to various drug–drug solid forms of pioglitazone hydrochloride (PGZ·HCl) and rosuvastatin calcium (RSV). Using NG, the coamorphous form was formed from the reaction of piogl...

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Detalles Bibliográficos
Autores principales: Muñoz Tecocoatzi, M. Fernanda, Páez-Franco, José C., Rubio-Carrasco, Kenneth, Núñez-Pineda, Alejandra, Dorazco-González, Alejandro, Fuentes-Noriega, Inés, Vilchis-Néstor, Alfredo R., Olvera, Lilian I., Morales-Morales, David, Germán-Acacio, Juan Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959797/
https://www.ncbi.nlm.nih.gov/pubmed/36839951
http://dx.doi.org/10.3390/pharmaceutics15020630

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