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Efficacy Validation of SARS-CoV-2-Inactivation and Viral Genome Stability in Saliva by a Guanidine Hydrochloride and Surfactant-Based Virus Lysis/Transport Buffer

To enhance biosafety and reliability in SARS-CoV-2 molecular diagnosis, virus lysis/transport buffers should inactivate the virus and preserve viral RNA under various conditions. Herein, we evaluated the SARS-CoV-2-inactivating activity of guanidine hydrochloride (GuHCl)- and surfactant (hexadecyltr...

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Detalles Bibliográficos
Autores principales: Komu, James Gitau, Jamsransuren, Dulamjav, Matsuda, Sachiko, Ogawa, Haruko, Takeda, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959814/
https://www.ncbi.nlm.nih.gov/pubmed/36851723
http://dx.doi.org/10.3390/v15020509