Cargando…

Melatonin-Assisted Cisplatin Suppresses Urinary Bladder Cancer Cell Proliferation and Growth through Inhibiting PrP(C)-Regulated Cell Stress and Cell Proliferation Signaling

This study investigated whether melatonin (Mel) would promote cisplatin to suppress the proliferation and growth of bladder cancer (BC) cells by inhibiting cellular prion protein (PrP(C))-mediated cell stress and cell proliferation signaling. An immunohistochemical staining of tissue arrays from BC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chih-Chao, Chuang, Fei-Chi, Chang, Chia-Lo, Huang, Chi-Ruei, Chen, Hong-Hwa, Yip, Hon-Kan, Chen, Yen-Ta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959909/ https://www.ncbi.nlm.nih.gov/pubmed/36834767 http://dx.doi.org/10.3390/ijms24043353

Ejemplares similares

Jagged2 progressively increased expression from Stage I to III of Bladder Cancer and Melatonin-mediated downregulation of Notch/Jagged2 suppresses the Bladder Tumorigenesis via inhibiting PI3K/AKT/mTOR/MMPs signaling
por: Chen, Yen-Ta, et al.
Publicado: (2020)

Combined melatonin-adipose derived mesenchymal stem cells therapy effectively protected the testis from testicular torsion-induced ischemia-reperfusion injury
por: Chen, Yen-Ta, et al.
Publicado: (2021)

Extracorporeal Shock Wave Therapy Protected the Functional and Architectural Integrity of Rodent Urinary Bladder against Ketamine-Induced Damage
por: Chen, Yen-Ta, et al.
Publicado: (2021)

Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
por: Sakudo, Akikazu, et al.
Publicado: (2015)

The Cellular Prion Protein PrP(c) Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins
por: Morel, Etienne, et al.
Publicado: (2008)

Extracorporeal Shock Wave Therapy Salvages Critical Limb Ischemia in B6 Mice through Upregulating Cell Proliferation Signaling and Angiogenesis
por: Sung, Pei-Hsun, et al.
Publicado: (2022)

Correction: The Cellular Prion Protein PrP(c) Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins
por: Morel, Etienne, et al.
Publicado: (2008)

Correction: The Cellular Prion Protein PrP(c) Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins
por: Morel, Etienne, et al.
Publicado: (2008)

PrP(C) from stem cells to cancer
por: Martin-Lannerée, Séverine, et al.
Publicado: (2014)

A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines
por: Jones, Daryl Rhys, et al.
Publicado: (2010)

Identifying critical sites of PrP(c)-PrP(Sc) interaction in prion-infected cells by dominant-negative inhibition
por: Taguchi, Yuzuru, et al.
Publicado: (2013)

Melatonin and hyperbaric oxygen therapies suppress colorectal carcinogenesis through pleiotropic effects and multifaceted mechanisms
por: Li, Yi-Chen, et al.
Publicado: (2021)

Liposome-siRNA-Peptide Complexes Cross the Blood-Brain Barrier and Significantly Decrease PrP(C) on Neuronal Cells and PrP(RES) in Infected Cell Cultures
por: Pulford, Bruce, et al.
Publicado: (2010)

The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018)

PrP Expression, PrP(Sc) Accumulation and Innervation of Splenic Compartments in Sheep Experimentally Infected with Scrapie
por: Sørby, Randi, et al.
Publicado: (2009)

Anti-Prion Drug mPPIg5 Inhibits PrP(C) Conversion to PrP(Sc)
por: McCarthy, James M., et al.
Publicado: (2013)

Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions
por: Miyazawa, Kohtaro, et al.
Publicado: (2015)

The native state of prion protein (PrP) directly inhibits formation of PrP-amyloid fibrils in vitro
por: Honda, Ryo P., et al.
Publicado: (2017)

Small Protease Sensitive Oligomers of PrP(Sc) in Distinct Human Prions Determine Conversion Rate of PrP(C)
por: Kim, Chae, et al.
Publicado: (2012)

Predicting the consequences of selecting on PrP genotypes on PrP frequencies, performance and inbreeding in commercial meat sheep populations
por: Man, Wing-Young N, et al.
Publicado: (2007)

PK-sensitive PrP(Sc) Is Infectious and Shares Basic Structural Features with PK-resistant PrP(Sc)
por: Sajnani, Gustavo, et al.
Publicado: (2012)

Familial CJD Associated PrP Mutants within Transmembrane Region Induced Ctm-PrP Retention in ER and Triggered Apoptosis by ER Stress in SH-SY5Y Cells
por: Wang, Xin, et al.
Publicado: (2011)

CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer
por: Chang, Chia-Lo, et al.
Publicado: (2021)

Hepatic (31)P‐magnetic resonance spectroscopy identified the impact of melatonin‐pretreated mitochondria in acute liver ischaemia‐reperfusion injury
por: Ko, Sheung‐Fat, et al.
Publicado: (2020)

PRP of T2DM Patient Immobilized on PCL Nanofibers Stimulate Endothelial Cells Proliferation
por: Solovieva, Anastasiya O., et al.
Publicado: (2023)

Glimepiride Reduces the Expression of PrP(C), Prevents PrP(Sc) Formation and Protects against Prion Mediated Neurotoxicity
por: Bate, Clive, et al.
Publicado: (2009)

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions
por: Barron, Rona M., et al.
Publicado: (2016)

Recombinant PrP(Sc) shares structural features with brain-derived PrP(Sc): Insights from limited proteolysis
por: Sevillano, Alejandro M., et al.
Publicado: (2018)

Exploration of the Main Sites for the Transformation of Normal Prion Protein (PrP(C)) into Pathogenic Prion Protein (PrP(sc))
por: Liu, Xi-Lin, et al.
Publicado: (2017)

Characterization of the cytokine profile of platelet rich plasma (PRP) and PRP-induced cell proliferation and migration: Upregulation of matrix metalloproteinase-1 and -9 in HaCaT cells
por: Park, Hong-Bum, et al.
Publicado: (2011)

Lipid Rafts and Clathrin Cooperate in the Internalization of PrP(C) in Epithelial FRT Cells
por: Sarnataro, Daniela, et al.
Publicado: (2009)

Influence of Mabs on PrP(Sc) Formation Using In Vitro and Cell-Free Systems
por: Chang, Binggong, et al.
Publicado: (2012)

PrP(C) Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells
por: Arkhipenko, Alexander, et al.
Publicado: (2016)

Na(+)/K(+)-ATPase Is Present in Scrapie-Associated Fibrils, Modulates PrP Misfolding In Vitro and Links PrP Function and Dysfunction
por: Graham, James F., et al.
Publicado: (2011)

Nanopore Analysis of Wild-Type and Mutant Prion Protein (PrP(C)): Single Molecule Discrimination and PrP(C) Kinetics
por: Jetha, Nahid N., et al.
Publicado: (2013)

Heterogeneity of Abnormal Prion Protein (PrP(Sc)) in Murine Scrapie Prions Determined by PrP(Sc)-Specific Monoclonal Antibodies
por: USHIKI-KAKU, Yuko, et al.
Publicado: (2013)

The ZIP5 Ectodomain Co-Localizes with PrP and May Acquire a PrP-Like Fold That Assembles into a Dimer
por: Pocanschi, Cosmin L., et al.
Publicado: (2013)

PrP(ST), a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease
por: Friedman-Levi, Yael, et al.
Publicado: (2013)

Low fraction of the 222K PrP variant in the protease-resistant moiety of PrP(res) in heterozygous scrapie positive goats
por: Mazza, Maria, et al.
Publicado: (2017)

Enhancement of binding avidity by bivalent binding enables PrP(Sc)-specific detection by anti-PrP monoclonal antibody 132
por: Suzuki, Akio, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nj1qj8lrdeis9gpvqsa7qvchib