Cargando…

Visualization of Nuclease- and Serum-Mediated Chromatin Degradation with DNA–Histone Mesostructures

This study analyzed the nuclease- and serum-driven degradation of millimeter-scale, circular DNA–histone mesostructures (DHMs). DHMs are bioengineered chromatin meshes of defined DNA and histone compositions designed as minimal mimetics of physiological extracellular chromatin structures, such as ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Wasielewski, Midori L., Nguyen, Katherine, Yalavarthi, Srilakshmi, Ekbote, Pallavi, Weerappuli, Priyan D., Knight, Jason S., Takayama, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959986/
https://www.ncbi.nlm.nih.gov/pubmed/36834634
http://dx.doi.org/10.3390/ijms24043222