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Visualization of Nuclease- and Serum-Mediated Chromatin Degradation with DNA–Histone Mesostructures

This study analyzed the nuclease- and serum-driven degradation of millimeter-scale, circular DNA–histone mesostructures (DHMs). DHMs are bioengineered chromatin meshes of defined DNA and histone compositions designed as minimal mimetics of physiological extracellular chromatin structures, such as ne...

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Detalles Bibliográficos
Autores principales:	Wasielewski, Midori L., Nguyen, Katherine, Yalavarthi, Srilakshmi, Ekbote, Pallavi, Weerappuli, Priyan D., Knight, Jason S., Takayama, Shuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959986/ https://www.ncbi.nlm.nih.gov/pubmed/36834634 http://dx.doi.org/10.3390/ijms24043222

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