What’s on the Other Side of the Gate: A Structural Perspective on DNA Gate Opening of Type IA and IIA DNA Topoisomerases

DNA topoisomerases have an essential role in resolving topological problems that arise due to the double-helical structure of DNA. They can recognise DNA topology and catalyse diverse topological reactions by cutting and re-joining DNA ends. Type IA and IIA topoisomerases, which work by strand passa...

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Detalles Bibliográficos
Autores principales: Vidmar, Vita, Vayssières, Marlène, Lamour, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960139/
https://www.ncbi.nlm.nih.gov/pubmed/36835394
http://dx.doi.org/10.3390/ijms24043986

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