Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance

Chemotherapy is one of the most important treatments for cancer therapy. However, chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy resistance, drugs become less effective or no longer effective at all. In recent years, long non-coding RNA metastasis-associated lung...

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Autores principales: Hou, Junhui, Zhang, Gong, Wang, Xia, Wang, Yuan, Wang, Kefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960193/
https://www.ncbi.nlm.nih.gov/pubmed/36829256
http://dx.doi.org/10.1186/s40364-023-00467-8
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author Hou, Junhui
Zhang, Gong
Wang, Xia
Wang, Yuan
Wang, Kefeng
author_facet Hou, Junhui
Zhang, Gong
Wang, Xia
Wang, Yuan
Wang, Kefeng
author_sort Hou, Junhui
collection PubMed
description Chemotherapy is one of the most important treatments for cancer therapy. However, chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy resistance, drugs become less effective or no longer effective at all. In recent years, long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been found to be associated with the development of chemotherapy resistance, suggesting that MALAT1 may be an important target to overcome chemotherapy resistance. In this review, we introduced the main mechanisms of chemotherapy resistance associated with MALAT1, which may provide new approaches for cancer treatment.
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spelling pubmed-99601932023-02-26 Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance Hou, Junhui Zhang, Gong Wang, Xia Wang, Yuan Wang, Kefeng Biomark Res Review Chemotherapy is one of the most important treatments for cancer therapy. However, chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy resistance, drugs become less effective or no longer effective at all. In recent years, long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been found to be associated with the development of chemotherapy resistance, suggesting that MALAT1 may be an important target to overcome chemotherapy resistance. In this review, we introduced the main mechanisms of chemotherapy resistance associated with MALAT1, which may provide new approaches for cancer treatment. BioMed Central 2023-02-24 /pmc/articles/PMC9960193/ /pubmed/36829256 http://dx.doi.org/10.1186/s40364-023-00467-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Hou, Junhui
Zhang, Gong
Wang, Xia
Wang, Yuan
Wang, Kefeng
Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance
title Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance
title_full Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance
title_fullStr Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance
title_full_unstemmed Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance
title_short Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance
title_sort functions and mechanisms of lncrna malat1 in cancer chemotherapy resistance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960193/
https://www.ncbi.nlm.nih.gov/pubmed/36829256
http://dx.doi.org/10.1186/s40364-023-00467-8
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