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Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial

(1) Background: In the mHeart trial, we showed that an eHealth intervention, mHeart, improved heart transplant (HTx) recipients’ adherence to immunosuppressive therapy compared with the standard of care. Herein, we present the analysis assessing whether mHeart reduces complication frequency and heal...

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Autores principales: Gomis-Pastor, Mar, Mirabet Perez, Sonia, De Dios Lopez, Anna, Brossa Loidi, Vicenç, Lopez Lopez, Laura, Pelegrin Cruz, Rebeca, Mangues Bafalluy, Mª Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960237/
https://www.ncbi.nlm.nih.gov/pubmed/36826572
http://dx.doi.org/10.3390/jcdd10020077
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author Gomis-Pastor, Mar
Mirabet Perez, Sonia
De Dios Lopez, Anna
Brossa Loidi, Vicenç
Lopez Lopez, Laura
Pelegrin Cruz, Rebeca
Mangues Bafalluy, Mª Antonia
author_facet Gomis-Pastor, Mar
Mirabet Perez, Sonia
De Dios Lopez, Anna
Brossa Loidi, Vicenç
Lopez Lopez, Laura
Pelegrin Cruz, Rebeca
Mangues Bafalluy, Mª Antonia
author_sort Gomis-Pastor, Mar
collection PubMed
description (1) Background: In the mHeart trial, we showed that an eHealth intervention, mHeart, improved heart transplant (HTx) recipients’ adherence to immunosuppressive therapy compared with the standard of care. Herein, we present the analysis assessing whether mHeart reduces complication frequency and healthcare resource use, and whether this reduction depends on patients’ adherence. (2) Methods: The mHeart was a single-center randomized-controlled trial (IIBSP-MHE-2014-55) in 134 adult HTx recipients (n = 71 intervention; n = 63 controls). The endpoints were mortality, complications, and resource use during follow-up (mean 1.6 ± 0.6 years). (3) Results: A significantly lower proportion of HTx recipients in mHeart had echocardiographic alteration (2.8% vs. 13.8%; p = 0.02), cardiovascular events (0.35% vs. 2.4%; p = 0.006), infections (17.2% vs. 56%; p = 0.03), and uncontrolled Hba1c (40.8% vs. 59.6%; p = 0.03) than controls. In addition, a significantly lower proportion of patients in the intervention needed hospital (32.4% vs. 56.9%; p = 0.004) or urgent admissions (16.9% vs. 41.4%; p = 0.002) and emergency room visits (50.7% vs. 69.0%; p = 0.03). Adherence status (measured by the self-reported SMAQ) influenced only controls regarding hospitalizations and emergency room visits. Differences were not significant on deaths (intervention 4.2% vs. control 9.5%; p = 0.4) (4) Conclusions: the mHeart strategy significantly reduced the occurrence of the studied post-transplant complications and the need for medical attention in HTx recipients. Adherence status influenced controls in their need for medical care.
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spelling pubmed-99602372023-02-26 Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial Gomis-Pastor, Mar Mirabet Perez, Sonia De Dios Lopez, Anna Brossa Loidi, Vicenç Lopez Lopez, Laura Pelegrin Cruz, Rebeca Mangues Bafalluy, Mª Antonia J Cardiovasc Dev Dis Article (1) Background: In the mHeart trial, we showed that an eHealth intervention, mHeart, improved heart transplant (HTx) recipients’ adherence to immunosuppressive therapy compared with the standard of care. Herein, we present the analysis assessing whether mHeart reduces complication frequency and healthcare resource use, and whether this reduction depends on patients’ adherence. (2) Methods: The mHeart was a single-center randomized-controlled trial (IIBSP-MHE-2014-55) in 134 adult HTx recipients (n = 71 intervention; n = 63 controls). The endpoints were mortality, complications, and resource use during follow-up (mean 1.6 ± 0.6 years). (3) Results: A significantly lower proportion of HTx recipients in mHeart had echocardiographic alteration (2.8% vs. 13.8%; p = 0.02), cardiovascular events (0.35% vs. 2.4%; p = 0.006), infections (17.2% vs. 56%; p = 0.03), and uncontrolled Hba1c (40.8% vs. 59.6%; p = 0.03) than controls. In addition, a significantly lower proportion of patients in the intervention needed hospital (32.4% vs. 56.9%; p = 0.004) or urgent admissions (16.9% vs. 41.4%; p = 0.002) and emergency room visits (50.7% vs. 69.0%; p = 0.03). Adherence status (measured by the self-reported SMAQ) influenced only controls regarding hospitalizations and emergency room visits. Differences were not significant on deaths (intervention 4.2% vs. control 9.5%; p = 0.4) (4) Conclusions: the mHeart strategy significantly reduced the occurrence of the studied post-transplant complications and the need for medical attention in HTx recipients. Adherence status influenced controls in their need for medical care. MDPI 2023-02-10 /pmc/articles/PMC9960237/ /pubmed/36826572 http://dx.doi.org/10.3390/jcdd10020077 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gomis-Pastor, Mar
Mirabet Perez, Sonia
De Dios Lopez, Anna
Brossa Loidi, Vicenç
Lopez Lopez, Laura
Pelegrin Cruz, Rebeca
Mangues Bafalluy, Mª Antonia
Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial
title Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial
title_full Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial
title_fullStr Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial
title_full_unstemmed Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial
title_short Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial
title_sort does an ehealth intervention reduce complications and healthcare resources? a mheart single-center randomized-controlled trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960237/
https://www.ncbi.nlm.nih.gov/pubmed/36826572
http://dx.doi.org/10.3390/jcdd10020077
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