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Optimization of Spray Drying Process Parameters for the Preparation of Inhalable Mannitol-Based Microparticles Using a Box-Behnken Experimental Design

Inhalation is used for local therapy of the lungs and as an alternative route for systemic drug delivery. Modern powder inhalation systems try to target the required site of action/absorption in the respiratory tract. Large porous particles (LPPs) with a size >5 μm and a low mass density (usually...

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Detalles Bibliográficos
Autores principales:	Karas, Jakub, Pavloková, Sylvie, Hořavová, Hana, Gajdziok, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960250/ https://www.ncbi.nlm.nih.gov/pubmed/36839819 http://dx.doi.org/10.3390/pharmaceutics15020496

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