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Peptidic Inhibitors and a Fluorescent Probe for the Selective Inhibition and Labelling of Factor XIIIa Transglutaminase

Factor XIIIa (FXIIIa) is a transglutaminase of major therapeutic interest for the development of anticoagulants due to its essential role in the blood coagulation cascade. While numerous FXIIIa inhibitors have been reported, they failed to reach clinical evaluation due to their lack of metabolic sta...

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Detalles Bibliográficos
Autores principales: Gates, Eric W. J., Mansour, Kian, Ebrahimi Samani, Sahar, Shad, Sammir, Kaartinen, Mari T., Keillor, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960274/
https://www.ncbi.nlm.nih.gov/pubmed/36838622
http://dx.doi.org/10.3390/molecules28041634

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