Valtrate, an iridoid compound in Valeriana, elicits anti-glioblastoma activity through inhibition of the PDGFRA/MEK/ERK signaling pathway

BACKGROUND: Valtrate, a natural compound isolated from the root of Valeriana, exhibits antitumor activity in many cancers through different mechanisms. However, its efficacy for the treatment of glioblastoma (GBM), a tumor type with a poor prognosis, has not yet been rigorously investigated. METHODS...

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Detalles Bibliográficos
Autores principales: Liu, Xuemeng, Hu, Yaotian, Xue, Zhiyi, Zhang, Xun, Liu, Xiaofei, Liu, Guowei, Wen, Muzi, Chen, Anjing, Huang, Bin, Li, Xingang, Yang, Ning, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960449/
https://www.ncbi.nlm.nih.gov/pubmed/36829235
http://dx.doi.org/10.1186/s12967-023-03984-0

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