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The Regulatory Mechanism of Transthyretin Irreversible Aggregation through Liquid-to-Solid Phase Transition

Transthyretin (TTR) aggregation and amyloid formation are associated with several ATTR diseases, such as senile systemic amyloidosis (SSA) and familial amyloid polyneuropathy (FAP). However, the mechanism that triggers the initial pathologic aggregation process of TTR remains largely elusive. Lately...

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Detalles Bibliográficos
Autores principales: Duan, Guangfei, Li, Yanqin, Ye, Meimei, Liu, Hexin, Wang, Ning, Luo, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960511/
https://www.ncbi.nlm.nih.gov/pubmed/36835140
http://dx.doi.org/10.3390/ijms24043729