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The Regulatory Mechanism of Transthyretin Irreversible Aggregation through Liquid-to-Solid Phase Transition
Transthyretin (TTR) aggregation and amyloid formation are associated with several ATTR diseases, such as senile systemic amyloidosis (SSA) and familial amyloid polyneuropathy (FAP). However, the mechanism that triggers the initial pathologic aggregation process of TTR remains largely elusive. Lately...
Autores principales: | Duan, Guangfei, Li, Yanqin, Ye, Meimei, Liu, Hexin, Wang, Ning, Luo, Shizhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960511/ https://www.ncbi.nlm.nih.gov/pubmed/36835140 http://dx.doi.org/10.3390/ijms24043729 |
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