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The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic

During the coronavirus pandemic 2019 (COVID-19), some studies showed differences in the profile of subjects presenting with acute coronary syndromes as well as in overall mortality due to the delay of presentation and other complications. The purpose of this study was to compare the profile and outc...

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Autores principales: Popa-Fotea, Nicoleta-Monica, Grigore, Iulia-Adelina, Calmac, Lucian, Mihai, Cosmin, Bataila, Vlad, Ploscaru, Vlad, Dragoescu, Bogdan, Moldovan, Horatiu, Busnatu, Stefan-Sebastian, Panaitescu, Eugenia, Iliuță, Luminita, Scafa-Udriște, Alexandru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960631/
https://www.ncbi.nlm.nih.gov/pubmed/36836002
http://dx.doi.org/10.3390/jcm12041467
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author Popa-Fotea, Nicoleta-Monica
Grigore, Iulia-Adelina
Calmac, Lucian
Mihai, Cosmin
Bataila, Vlad
Ploscaru, Vlad
Dragoescu, Bogdan
Moldovan, Horatiu
Busnatu, Stefan-Sebastian
Panaitescu, Eugenia
Iliuță, Luminita
Scafa-Udriște, Alexandru
author_facet Popa-Fotea, Nicoleta-Monica
Grigore, Iulia-Adelina
Calmac, Lucian
Mihai, Cosmin
Bataila, Vlad
Ploscaru, Vlad
Dragoescu, Bogdan
Moldovan, Horatiu
Busnatu, Stefan-Sebastian
Panaitescu, Eugenia
Iliuță, Luminita
Scafa-Udriște, Alexandru
author_sort Popa-Fotea, Nicoleta-Monica
collection PubMed
description During the coronavirus pandemic 2019 (COVID-19), some studies showed differences in the profile of subjects presenting with acute coronary syndromes as well as in overall mortality due to the delay of presentation and other complications. The purpose of this study was to compare the profile and outcomes, with emphasis on all-cause in-hospital mortality, of ST-elevation myocardial infarction (STEMI) subjects presenting to the emergency department during the pandemic period compared with a control group from the previous year, 2019. The study enrolled 2011 STEMI cases, which were divided into two groups—pre-pandemic (2019–2020) and pandemic period (2020–2022). Hospital admissions for a STEMI diagnosis sharply decreased during the COVID-19 period by 30.26% during the first year and 25.4% in the second year. This trend was paralleled by a significant increase in all-cause in-hospital mortality: 11.5% in the pandemic period versus 8.1% in the previous year. There was a significant association between SARS-CoV-2 positivity and all-cause in-hospital mortality, but no correlation was found between COVID-19 diagnosis and the type of revascularization. However, the profile of subjects presenting with STEMI did not change over time during the pandemic; their demographic and comorbid characteristics remained similar.
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spelling pubmed-99606312023-02-26 The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic Popa-Fotea, Nicoleta-Monica Grigore, Iulia-Adelina Calmac, Lucian Mihai, Cosmin Bataila, Vlad Ploscaru, Vlad Dragoescu, Bogdan Moldovan, Horatiu Busnatu, Stefan-Sebastian Panaitescu, Eugenia Iliuță, Luminita Scafa-Udriște, Alexandru J Clin Med Article During the coronavirus pandemic 2019 (COVID-19), some studies showed differences in the profile of subjects presenting with acute coronary syndromes as well as in overall mortality due to the delay of presentation and other complications. The purpose of this study was to compare the profile and outcomes, with emphasis on all-cause in-hospital mortality, of ST-elevation myocardial infarction (STEMI) subjects presenting to the emergency department during the pandemic period compared with a control group from the previous year, 2019. The study enrolled 2011 STEMI cases, which were divided into two groups—pre-pandemic (2019–2020) and pandemic period (2020–2022). Hospital admissions for a STEMI diagnosis sharply decreased during the COVID-19 period by 30.26% during the first year and 25.4% in the second year. This trend was paralleled by a significant increase in all-cause in-hospital mortality: 11.5% in the pandemic period versus 8.1% in the previous year. There was a significant association between SARS-CoV-2 positivity and all-cause in-hospital mortality, but no correlation was found between COVID-19 diagnosis and the type of revascularization. However, the profile of subjects presenting with STEMI did not change over time during the pandemic; their demographic and comorbid characteristics remained similar. MDPI 2023-02-12 /pmc/articles/PMC9960631/ /pubmed/36836002 http://dx.doi.org/10.3390/jcm12041467 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Popa-Fotea, Nicoleta-Monica
Grigore, Iulia-Adelina
Calmac, Lucian
Mihai, Cosmin
Bataila, Vlad
Ploscaru, Vlad
Dragoescu, Bogdan
Moldovan, Horatiu
Busnatu, Stefan-Sebastian
Panaitescu, Eugenia
Iliuță, Luminita
Scafa-Udriște, Alexandru
The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic
title The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic
title_full The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic
title_fullStr The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic
title_full_unstemmed The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic
title_short The Profile and All-Cause In-Hospital Mortality Dynamics of St-Segment Elevation Myocardial Infarction Patients during the Two Years of the COVID-19 Pandemic
title_sort profile and all-cause in-hospital mortality dynamics of st-segment elevation myocardial infarction patients during the two years of the covid-19 pandemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960631/
https://www.ncbi.nlm.nih.gov/pubmed/36836002
http://dx.doi.org/10.3390/jcm12041467
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