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Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application

The exceptional characteristics of bio-synthesized copper oxide nanoparticles (CuO NPs), including high surface-to-volume ratio and high-profit strength, are of tremendous interest. CuO NPs have cytotoxic, catalytic, antibacterial, and antioxidant properties. Fruit peel extract has been recommended...

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Autores principales: Rajamohan, Rajaram, Raorane, Chaitany Jayprakash, Kim, Seong-Cheol, Ashokkumar, Sekar, Lee, Yong Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960782/
https://www.ncbi.nlm.nih.gov/pubmed/36838156
http://dx.doi.org/10.3390/mi14020456
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author Rajamohan, Rajaram
Raorane, Chaitany Jayprakash
Kim, Seong-Cheol
Ashokkumar, Sekar
Lee, Yong Rok
author_facet Rajamohan, Rajaram
Raorane, Chaitany Jayprakash
Kim, Seong-Cheol
Ashokkumar, Sekar
Lee, Yong Rok
author_sort Rajamohan, Rajaram
collection PubMed
description The exceptional characteristics of bio-synthesized copper oxide nanoparticles (CuO NPs), including high surface-to-volume ratio and high-profit strength, are of tremendous interest. CuO NPs have cytotoxic, catalytic, antibacterial, and antioxidant properties. Fruit peel extract has been recommended as a valuable alternative method due to the advantages of economic prospects, environment-friendliness, improved biocompatibility, and high biological activities, such as antioxidant and antimicrobial activities, as many physical and chemical methods have been applied to synthesize metal oxide NPs. In the presence of apple peel extract and microwave (MW) irradiation, CuO NPs are produced from the precursor CuCl(2). 2H(2)O. With the help of TEM analysis, and BET surface area, the average sizes of the obtained NPs are found to be 25–40 nm. For use in antimicrobial applications, CuO NPs are appropriate. Disk diffusion tests were used to study the bactericidal impact in relation to the diameter of the inhibition zone, and an intriguing antibacterial activity was confirmed on both the Gram-positive bacterial pathogen Staphylococcus aureus and Gram-negative bacterial pathogen Escherichia coli. Moreover, CuO NPs did not have any toxic effect on seed germination. Thus, this study provides an environmentally friendly material and provides a variety of advantages for biomedical applications and environmental applications.
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spelling pubmed-99607822023-02-26 Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application Rajamohan, Rajaram Raorane, Chaitany Jayprakash Kim, Seong-Cheol Ashokkumar, Sekar Lee, Yong Rok Micromachines (Basel) Article The exceptional characteristics of bio-synthesized copper oxide nanoparticles (CuO NPs), including high surface-to-volume ratio and high-profit strength, are of tremendous interest. CuO NPs have cytotoxic, catalytic, antibacterial, and antioxidant properties. Fruit peel extract has been recommended as a valuable alternative method due to the advantages of economic prospects, environment-friendliness, improved biocompatibility, and high biological activities, such as antioxidant and antimicrobial activities, as many physical and chemical methods have been applied to synthesize metal oxide NPs. In the presence of apple peel extract and microwave (MW) irradiation, CuO NPs are produced from the precursor CuCl(2). 2H(2)O. With the help of TEM analysis, and BET surface area, the average sizes of the obtained NPs are found to be 25–40 nm. For use in antimicrobial applications, CuO NPs are appropriate. Disk diffusion tests were used to study the bactericidal impact in relation to the diameter of the inhibition zone, and an intriguing antibacterial activity was confirmed on both the Gram-positive bacterial pathogen Staphylococcus aureus and Gram-negative bacterial pathogen Escherichia coli. Moreover, CuO NPs did not have any toxic effect on seed germination. Thus, this study provides an environmentally friendly material and provides a variety of advantages for biomedical applications and environmental applications. MDPI 2023-02-15 /pmc/articles/PMC9960782/ /pubmed/36838156 http://dx.doi.org/10.3390/mi14020456 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rajamohan, Rajaram
Raorane, Chaitany Jayprakash
Kim, Seong-Cheol
Ashokkumar, Sekar
Lee, Yong Rok
Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application
title Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application
title_full Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application
title_fullStr Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application
title_full_unstemmed Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application
title_short Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application
title_sort novel microwave synthesis of copper oxide nanoparticles and appraisal of the antibacterial application
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960782/
https://www.ncbi.nlm.nih.gov/pubmed/36838156
http://dx.doi.org/10.3390/mi14020456
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