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Can Resveratrol Influence the Activity of 11β-Hydroxysteroid Dehydrogenase Type 1? A Combined In Silico and In Vivo Study

The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) is an NADPH-dependent reductase, responsible for the activation of cortisol by reducing cortisone. Resveratrol (RES), a type of natural polyphenol, is reported to be able to slow the progression of cancer and cardiovascular disease and i...

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Detalles Bibliográficos
Autores principales: Novak, Jurica, Tseilikman, Vadim E., Tseilikman, Olga B., Lazuko, Svetlana S., Belyeva, Lyudmila E., Rahmani, Azam, Fedotova, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960807/
https://www.ncbi.nlm.nih.gov/pubmed/37259398
http://dx.doi.org/10.3390/ph16020251