Cargando…

Evaluation of Rhenium and Technetium-99m Complexes Bearing Quinazoline Derivatives as Potential EGFR Agents

Τhe Epidermal Growth Factor Receptor tyrosine kinase inhibitor (EGFR-TKI) 6-amino-4-[(3-bromophenyl) amino]quinazoline was derivatized with 6-bromohexanoyl-chloride and coupled with the tridentate chelating agents N-(2-pyridylmethyl) aminoethyl acetic acid (PAMA) and L(+)-cysteine bearing the donor...

Descripción completa

Detalles Bibliográficos
Autores principales: Makrypidi, Konstantina, Kiritsis, Christos, Roupa, Ioanna, Triantopoulou, Sotiria, Shegani, Antonio, Paravatou-Petsotas, Maria, Chiotellis, Aristeidis, Pelecanou, Maria, Papadopoulos, Minas, Pirmettis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960821/
https://www.ncbi.nlm.nih.gov/pubmed/36838773
http://dx.doi.org/10.3390/molecules28041786