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Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status

The objectives of this study were to characterize dietary fiber (DF) intake in patients with ankylosing spondylitis (AS), to assess whether DF intake affects disease activity in AS, and to investigate the effect of DF intake on disease activity in AS in the context of functional bowel disease (FBD)...

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Autores principales: Song, Chuan, Wang, Lei, Ji, Xiaojian, Wang, Yiwen, Hu, Lidong, Liu, Xingkang, Zhang, Jiaxin, Liao, Simin, Yan, Yishu, Zhu, Jian, Huang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960917/
https://www.ncbi.nlm.nih.gov/pubmed/36836155
http://dx.doi.org/10.3390/jcm12041621
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author Song, Chuan
Wang, Lei
Ji, Xiaojian
Wang, Yiwen
Hu, Lidong
Liu, Xingkang
Zhang, Jiaxin
Liao, Simin
Yan, Yishu
Zhu, Jian
Huang, Feng
author_facet Song, Chuan
Wang, Lei
Ji, Xiaojian
Wang, Yiwen
Hu, Lidong
Liu, Xingkang
Zhang, Jiaxin
Liao, Simin
Yan, Yishu
Zhu, Jian
Huang, Feng
author_sort Song, Chuan
collection PubMed
description The objectives of this study were to characterize dietary fiber (DF) intake in patients with ankylosing spondylitis (AS), to assess whether DF intake affects disease activity in AS, and to investigate the effect of DF intake on disease activity in AS in the context of functional bowel disease (FBD) symptoms. We recruited 165 patients with AS and divided them into two groups according to whether they had a high DF intake > 25 g/d to investigate the characteristics of people with high DF intake. Some 72 of the 165 AS patients (43%) met the criteria for high DF intake, which was more common in patients with negative FBD symptoms (68%). Data analysis revealed that DF intake was negatively associated with AS disease activity and did not differ statistically significantly from FBD symptoms. Multivariate adjusted models were used to explore the effect of DF intake on AS disease activity. ASDAS-CRP and BASDAI were stable and negatively correlated across models in both groups with and without FBD symptoms. Thus, DF intake positively affected disease activity in patients with AS. ASDAS-CRP and BASDAI were negatively correlated with DF intake.
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spelling pubmed-99609172023-02-26 Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status Song, Chuan Wang, Lei Ji, Xiaojian Wang, Yiwen Hu, Lidong Liu, Xingkang Zhang, Jiaxin Liao, Simin Yan, Yishu Zhu, Jian Huang, Feng J Clin Med Article The objectives of this study were to characterize dietary fiber (DF) intake in patients with ankylosing spondylitis (AS), to assess whether DF intake affects disease activity in AS, and to investigate the effect of DF intake on disease activity in AS in the context of functional bowel disease (FBD) symptoms. We recruited 165 patients with AS and divided them into two groups according to whether they had a high DF intake > 25 g/d to investigate the characteristics of people with high DF intake. Some 72 of the 165 AS patients (43%) met the criteria for high DF intake, which was more common in patients with negative FBD symptoms (68%). Data analysis revealed that DF intake was negatively associated with AS disease activity and did not differ statistically significantly from FBD symptoms. Multivariate adjusted models were used to explore the effect of DF intake on AS disease activity. ASDAS-CRP and BASDAI were stable and negatively correlated across models in both groups with and without FBD symptoms. Thus, DF intake positively affected disease activity in patients with AS. ASDAS-CRP and BASDAI were negatively correlated with DF intake. MDPI 2023-02-17 /pmc/articles/PMC9960917/ /pubmed/36836155 http://dx.doi.org/10.3390/jcm12041621 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Song, Chuan
Wang, Lei
Ji, Xiaojian
Wang, Yiwen
Hu, Lidong
Liu, Xingkang
Zhang, Jiaxin
Liao, Simin
Yan, Yishu
Zhu, Jian
Huang, Feng
Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status
title Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status
title_full Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status
title_fullStr Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status
title_full_unstemmed Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status
title_short Dietary Fiber Intake Influences Changes in Ankylosing Spondylitis Disease Status
title_sort dietary fiber intake influences changes in ankylosing spondylitis disease status
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9960917/
https://www.ncbi.nlm.nih.gov/pubmed/36836155
http://dx.doi.org/10.3390/jcm12041621
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