Development of a Library of Disulfide Bond-Containing Cationic Lipids for mRNA Delivery

Lipid nanoparticles (LNPs) are the commonly used delivery tools for messenger RNA (mRNA) therapy and play an indispensable role in the success of COVID-19 mRNA vaccines. Ionizable cationic lipids are the most important component in LNPs. Herein, we developed a series of new ionizable lipids featurin...

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Detalles Bibliográficos
Autores principales: Shen, Zhigao, Liu, Cong, Wang, Ziqian, Xie, Fengfei, Liu, Xingwu, Dong, Lingkai, Pan, Xuehua, Zeng, Chen, Wang, Peng George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961079/
https://www.ncbi.nlm.nih.gov/pubmed/36839799
http://dx.doi.org/10.3390/pharmaceutics15020477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961079/
https://www.ncbi.nlm.nih.gov/pubmed/36839799
http://dx.doi.org/10.3390/pharmaceutics15020477

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