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Advances in Plant Epigenome Editing Research and Its Application in Plants
Plant epistatic regulation is the DNA methylation, non-coding RNA regulation, and histone modification of gene sequences without altering the genome sequence, thus regulating gene expression patterns and the growth process of plants to produce heritable changes. Epistatic regulation in plants can re...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961165/ https://www.ncbi.nlm.nih.gov/pubmed/36834852 http://dx.doi.org/10.3390/ijms24043442 |
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author | Qi, Qiaoyun Hu, Bichun Jiang, Weiyu Wang, Yixiong Yan, Jinjiao Ma, Fengwang Guan, Qingmei Xu, Jidi |
author_facet | Qi, Qiaoyun Hu, Bichun Jiang, Weiyu Wang, Yixiong Yan, Jinjiao Ma, Fengwang Guan, Qingmei Xu, Jidi |
author_sort | Qi, Qiaoyun |
collection | PubMed |
description | Plant epistatic regulation is the DNA methylation, non-coding RNA regulation, and histone modification of gene sequences without altering the genome sequence, thus regulating gene expression patterns and the growth process of plants to produce heritable changes. Epistatic regulation in plants can regulate plant responses to different environmental stresses, regulate fruit growth and development, etc. Genome editing can effectively improve plant genetic efficiency by targeting the design and efficient editing of genome-specific loci with specific nucleases, such as zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALEN), and clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 (CRISPR/Cas9). As research progresses, the CRISPR/Cas9 system has been widely used in crop breeding, gene expression, and epistatic modification due to its high editing efficiency and rapid translation of results. In this review, we summarize the recent progress of CRISPR/Cas9 in epigenome editing and look forward to the future development direction of this system in plant epigenetic modification to provide a reference for the application of CRISPR/Cas9 in genome editing. |
format | Online Article Text |
id | pubmed-9961165 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99611652023-02-26 Advances in Plant Epigenome Editing Research and Its Application in Plants Qi, Qiaoyun Hu, Bichun Jiang, Weiyu Wang, Yixiong Yan, Jinjiao Ma, Fengwang Guan, Qingmei Xu, Jidi Int J Mol Sci Review Plant epistatic regulation is the DNA methylation, non-coding RNA regulation, and histone modification of gene sequences without altering the genome sequence, thus regulating gene expression patterns and the growth process of plants to produce heritable changes. Epistatic regulation in plants can regulate plant responses to different environmental stresses, regulate fruit growth and development, etc. Genome editing can effectively improve plant genetic efficiency by targeting the design and efficient editing of genome-specific loci with specific nucleases, such as zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALEN), and clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 (CRISPR/Cas9). As research progresses, the CRISPR/Cas9 system has been widely used in crop breeding, gene expression, and epistatic modification due to its high editing efficiency and rapid translation of results. In this review, we summarize the recent progress of CRISPR/Cas9 in epigenome editing and look forward to the future development direction of this system in plant epigenetic modification to provide a reference for the application of CRISPR/Cas9 in genome editing. MDPI 2023-02-08 /pmc/articles/PMC9961165/ /pubmed/36834852 http://dx.doi.org/10.3390/ijms24043442 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Qi, Qiaoyun Hu, Bichun Jiang, Weiyu Wang, Yixiong Yan, Jinjiao Ma, Fengwang Guan, Qingmei Xu, Jidi Advances in Plant Epigenome Editing Research and Its Application in Plants |
title | Advances in Plant Epigenome Editing Research and Its Application in Plants |
title_full | Advances in Plant Epigenome Editing Research and Its Application in Plants |
title_fullStr | Advances in Plant Epigenome Editing Research and Its Application in Plants |
title_full_unstemmed | Advances in Plant Epigenome Editing Research and Its Application in Plants |
title_short | Advances in Plant Epigenome Editing Research and Its Application in Plants |
title_sort | advances in plant epigenome editing research and its application in plants |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961165/ https://www.ncbi.nlm.nih.gov/pubmed/36834852 http://dx.doi.org/10.3390/ijms24043442 |
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