Cargando…

DNase I and Sivelestat Ameliorate Experimental Hindlimb Ischemia-Reperfusion Injury by Eliminating Neutrophil Extracellular Traps

PURPOSE: Neutrophil extracellular traps (NETs) play an important role in ischemia-reperfusion injury (IRI) of the hindlimb. The aim of this study was to investigate the effect of recombinant DNase I and sivelestat in eliminating NETs and their effects on IRI limbs. PATIENTS AND METHODS: An air pump...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Chun-Lian, Wang, Yan, Jiang, Qi-Lan, Zeng, Yang, Yao, Qing-Ping, Liu, Xing, Li, Tao, Jiang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961174/ https://www.ncbi.nlm.nih.gov/pubmed/36852300 http://dx.doi.org/10.2147/JIR.S396049

Ejemplares similares

Neutrophil Extracellular Traps-DNase Balance and Autoimmunity
por: Angeletti, Andrea, et al.
Publicado: (2021)

Neutrophil extracellular traps and DNases orchestrate formation of peritoneal adhesions
por: Elrod, Julia, et al.
Publicado: (2023)

Physical Exercise Promotes DNase Activity Enhancing the Capacity to Degrade Neutrophil Extracellular Traps
por: Ondracek, Anna S., et al.
Publicado: (2022)

The role of extracellular traps in ischemia reperfusion injury
por: Zhang, Feilong, et al.
Publicado: (2022)

DNase I targeted degradation of neutrophil extracellular traps to reduce the damage on IgAV rat
por: Chen, Xiu-Qi, et al.
Publicado: (2023)

The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass
por: Pan, Tuo, et al.
Publicado: (2023)

Recombinant human DNase-I improves acute respiratory distress syndrome via neutrophil extracellular trap degradation
por: Jarrahi, Abbas, et al.
Publicado: (2023)

Exogenous Local Hyperthermia at 41℃ Is Effective to Eliminate Mouse Model of Sporotrichosis, Independent of Neutrophil Extracellular Traps Formation
por: Wang, Ya-Lan, et al.
Publicado: (2021)

The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats
por: Li, Guofu, et al.
Publicado: (2016)

Corrigendum: The neutrophil elastase inhibitor, Sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass
por: Pan, Tuo, et al.
Publicado: (2023)

Enhanced autophagy alleviates injury during hindlimb ischemia/reperfusion in mice
por: Liu, Chenshu, et al.
Publicado: (2019)

Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors
por: Crocetti, Letizia, et al.
Publicado: (2020)

Genetically Engineered Cellular Nanovesicle as Targeted DNase I Delivery System for the Clearance of Neutrophil Extracellular Traps in Acute Lung Injury
por: Du, Yang, et al.
Publicado: (2023)

Effects of FTY720 on Lung Injury Induced by Hindlimb Ischemia Reperfusion in Rats
por: Wang, Liangrong, et al.
Publicado: (2017)

Exaggerated blood pressure response to static exercise in hindlimb ischemia-reperfusion
por: Qin, Lu, et al.
Publicado: (2022)

Methylene Blue Attenuates Lung Injury Induced by Hindlimb Ischemia Reperfusion in Rats
por: Wang, Liangrong, et al.
Publicado: (2018)

Batroxobin accelerated tissue repair via neutrophil extracellular trap regulation and defibrinogenation in a murine ischemic hindlimb model
por: Masuda, Haruchika, et al.
Publicado: (2019)

Reduced Neutrophil Extracellular Trap Formation During Ischemia Reperfusion Injury in C3 KO Mice: C3 Requirement for NETs Release
por: Wu, Xiaoting, et al.
Publicado: (2022)

Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion
por: Aune, Sverre E., et al.
Publicado: (2013)

Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats
por: Sun, Yali, et al.
Publicado: (2022)

Tramadol Alleviates Myocardial Injury Induced by Acute Hindlimb Ischemia Reperfusion in Rats
por: Takhtfooladi, Hamed Ashrafzadeh, et al.
Publicado: (2015)

Protective effects of remote ischemic preconditioning in rat hindlimb on ischemia- reperfusion injury★
por: Zhang, Ying, et al.
Publicado: (2012)

Myogenic progenitor cell transplantation for muscle regeneration following hindlimb ischemia and reperfusion
por: Messner, Franka, et al.
Publicado: (2021)

Clinical utility of the neutrophil elastase inhibitor sivelestat for the treatment of acute respiratory distress syndrome
por: Aikawa, Naoki, et al.
Publicado: (2014)

Preclinical efficacy investigation of human neutrophil elastase inhibitor sivelestat in animal model of psoriasis
por: Zhukov, A. S., et al.
Publicado: (2021)

Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage
por: Witsch, Jens, et al.
Publicado: (2022)

GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion
por: Zhao, Chen, et al.
Publicado: (2023)

DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury
por: Wang, Shikai, et al.
Publicado: (2018)

DNase-1 Treatment Exerts Protective Effects in Neurogenic Pulmonary Edema via Regulating the Neutrophil Extracellular Traps after Subarachnoid Hemorrhage in Mice
por: Wu, Xinyan, et al.
Publicado: (2022)

Dexamethasone Protects Against Tourniquet-Induced Acute Ischemia-Reperfusion Injury in Mouse Hindlimb
por: Corrick, Ryan M., et al.
Publicado: (2018)

Candida Administration Worsens Neutrophil Extracellular Traps in Renal Ischemia Reperfusion Injury Mice: An Impact of Gut Fungi on Acute Kidney Injury
por: Saithong, Supichcha, et al.
Publicado: (2022)

Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis
por: Miyoshi, Seigo, et al.
Publicado: (2013)

Neutrophil Elastase Inhibitor Sivelestat Attenuates Myocardial Injury after Cardioplegic Arrest in Rat Hearts
por: Fujii, Masahiro, et al.
Publicado: (2019)

Murine Model of Hindlimb Ischemia
por: Niiyama, Hiroshi, et al.
Publicado: (2009)

Identification of renal ischemia reperfusion injury subtypes and predictive strategies for delayed graft function and graft survival based on neutrophil extracellular trap-related genes
por: Wu, Jiyue, et al.
Publicado: (2022)

Neutrophil extracellular traps induce the bone erosion of gout
por: Jia, Ertao, et al.
Publicado: (2022)

Neutrophil Extracellular Traps in Candida albicans Infection
por: He, Yufei, et al.
Publicado: (2022)

The emerging role of neutrophil extracellular traps in fungal infection
por: Liang, Chuting, et al.
Publicado: (2022)

Neutrophil Extracellular Traps and Microcrystals
por: Rada, Balázs
Publicado: (2017)

Neutrophil Extracellular Traps in Periodontitis
por: Magán-Fernández, Antonio, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_phv95rd2qnknlu4oui9p6vb86g