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Activation of Endothelial Large Conductance Potassium Channels Protects against TNF-α-Induced Inflammation

Elevated TNF-α levels in serum and broncho-alveolar lavage fluid of acute lung injury patients correlate with mortality rates. We hypothesized that pharmacological plasma membrane potential (Em) hyperpolarization protects against TNF-α-induced CCL-2 and IL-6 secretion from human pulmonary endothelia...

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Detalles Bibliográficos
Autores principales:	Zyrianova, Tatiana, Zou, Kathlyn, Lopez, Benjamin, Liao, Andy, Gu, Charles, Olcese, Riccardo, Schwingshackl, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961193/ https://www.ncbi.nlm.nih.gov/pubmed/36835507 http://dx.doi.org/10.3390/ijms24044087

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