Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation

Despite promising clinical results in osteochondral defect repair, a recently developed bi-layered collagen/collagen-magnesium-hydroxyapatite scaffold has demonstrated less optimal subchondral bone repair. This study aimed to improve the bone repair potential of this scaffold by adsorbing bone morph...

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Detalles Bibliográficos
Autores principales: Xu, Jietao, Fahmy-Garcia, Shorouk, Wesdorp, Marinus A., Kops, Nicole, Forte, Lucia, De Luca, Claudio, Misciagna, Massimiliano Maraglino, Dolcini, Laura, Filardo, Giuseppe, Labberté, Margot, Vancíková, Karin, Kok, Joeri, van Rietbergen, Bert, Nickel, Joachim, Farrell, Eric, Brama, Pieter A. J., van Osch, Gerjo J. V. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961206/
https://www.ncbi.nlm.nih.gov/pubmed/36826910
http://dx.doi.org/10.3390/jfb14020111

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