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Ca(2+)-Dependent and -Independent Calmodulin Binding to the Cytoplasmic Loop of Gap Junction Connexins

Ca(2+)/calmodulin (Ca(2+)/CaM) interaction with connexins (Cx) is well-established; however, the mechanistic basis of regulation of gap junction function by Ca(2+)/CaM is not fully understood. Ca(2+)/CaM is predicted to bind to a domain in the C-terminal portion of the intracellular loop (CL2) in th...

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Detalles Bibliográficos
Autores principales: Tran, Oanh, Kerruth, Silke, Coates, Catherine, Kaur, Hansween, Peracchia, Camillo, Carter, Tom, Török, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961272/
https://www.ncbi.nlm.nih.gov/pubmed/36835569
http://dx.doi.org/10.3390/ijms24044153