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Efflux Pump (QacA, QacB, and QacC) and β-Lactamase Inhibitors? An Evaluation of 1,8-Naphthyridines against Staphylococcus aureus Strains

The bacterial species Staphylococcus aureus presents a variety of resistance mechanisms, among which the expression of β-lactamases and efflux pumps stand out for providing a significant degree of resistance to clinically relevant antibiotics. The 1,8-naphthyridines are nitrogen heterocycles with a...

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Detalles Bibliográficos
Autores principales: Oliveira-Tintino, Cícera Datiane de Morais, Tintino, Saulo Relison, Justino de Araújo, Ana Carolina, dos Santos Barbosa, Cristina Rodrigues, Ramos Freitas, Priscilla, de Araújo Neto, José Bezerra, Begnini, Iêda Maria, Rebelo, Ricardo Andrade, da Silva, Luiz Everson, Mireski, Sandro Lucio, Nasato, Michele Caroline, Krautler, Maria Isabel Lacowicz, Barreto, Humberto Medeiros, Ribeiro-Filho, Jaime, de Menezes, Irwin Rose Alencar, Coutinho, Henrique Douglas Melo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961278/
https://www.ncbi.nlm.nih.gov/pubmed/36838807
http://dx.doi.org/10.3390/molecules28041819

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