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A Natural Glucan from Black Bean Inhibits Cancer Cell Proliferation via PI3K-Akt and MAPK Pathway

A natural α-1,6-glucan named BBWPW was identified from black beans. Cell viability assay showed that BBWPW inhibited the proliferation of different cancer cells, especially HeLa cells. Flow cytometry analysis indicated that BBWPW suppressed the HeLa cell cycle in the G2/M phase. Consistently, RT-PCR...

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Detalles Bibliográficos
Autores principales: Li, Peng, Hu, Yihua, Zhan, Lingmin, He, Jiaqi, Lu, Jingwu, Gao, Chunyan, Du, Weijun, Yue, Aiqin, Zhao, Jinzhong, Zhang, Wuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961350/
https://www.ncbi.nlm.nih.gov/pubmed/36838963
http://dx.doi.org/10.3390/molecules28041971