Hypericum perforatum L. Nanoemulsion Mitigates Cisplatin-Induced Chemobrain via Reducing Neurobehavioral Alterations, Oxidative Stress, Neuroinflammation, and Apoptosis in Adult Rats

Cisplatin (Cis) is a potent chemotherapeutic agent; however, it is linked with oxidative stress, inflammation, and apoptosis, which may harmfully affect the brain. Hypericum perforatum L. (HP L.) is a strong medicinal plant, but its hydrophobic polyphenolic compounds limit its activity. Therefore, o...

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Detalles Bibliográficos
Autores principales: Khalil, Heba M. A., El Henafy, Hanan M. A., Khalil, Islam A., Bakr, Alaa F., Fahmy, Mohamed I., Younis, Nancy S., El-Shiekh, Riham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961500/
https://www.ncbi.nlm.nih.gov/pubmed/36851034
http://dx.doi.org/10.3390/toxics11020159

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