Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use

Rising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less is known about the mRNA vaccines. This report docum...

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Autores principales: Frommeyer, Timothy C., Wu, Tongfan, Gilbert, Michael M., Brittain, Garrett V., Fuqua, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961502/
https://www.ncbi.nlm.nih.gov/pubmed/36836821
http://dx.doi.org/10.3390/life13020464
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author Frommeyer, Timothy C.
Wu, Tongfan
Gilbert, Michael M.
Brittain, Garrett V.
Fuqua, Stephen P.
author_facet Frommeyer, Timothy C.
Wu, Tongfan
Gilbert, Michael M.
Brittain, Garrett V.
Fuqua, Stephen P.
author_sort Frommeyer, Timothy C.
collection PubMed
description Rising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less is known about the mRNA vaccines. This report documents a case of CVST in a 32-year-old female patient who received her second Pfizer mRNA COVID-19 vaccination 16 days prior to hospital admission and had started oral combined contraceptives approximately 4 months beforehand. Clinicians should be cognizant of the possibility that mRNA vaccines, when combined with other risk factors like oral contraceptive pill use, may enhance one’s hypercoagulable status.
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spelling pubmed-99615022023-02-26 Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use Frommeyer, Timothy C. Wu, Tongfan Gilbert, Michael M. Brittain, Garrett V. Fuqua, Stephen P. Life (Basel) Case Report Rising concerns of cerebral venous sinus thrombosis (CVST) and other forms of venous thromboembolism have been associated with the SARS-CoV-2 vaccinations. Adverse effects with vector-based vaccines are well documented in the literature, while less is known about the mRNA vaccines. This report documents a case of CVST in a 32-year-old female patient who received her second Pfizer mRNA COVID-19 vaccination 16 days prior to hospital admission and had started oral combined contraceptives approximately 4 months beforehand. Clinicians should be cognizant of the possibility that mRNA vaccines, when combined with other risk factors like oral contraceptive pill use, may enhance one’s hypercoagulable status. MDPI 2023-02-07 /pmc/articles/PMC9961502/ /pubmed/36836821 http://dx.doi.org/10.3390/life13020464 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Frommeyer, Timothy C.
Wu, Tongfan
Gilbert, Michael M.
Brittain, Garrett V.
Fuqua, Stephen P.
Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use
title Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use
title_full Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use
title_fullStr Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use
title_full_unstemmed Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use
title_short Cerebral Venous Sinus Thrombosis Following an mRNA COVID-19 Vaccination and Recent Oral Contraceptive Use
title_sort cerebral venous sinus thrombosis following an mrna covid-19 vaccination and recent oral contraceptive use
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961502/
https://www.ncbi.nlm.nih.gov/pubmed/36836821
http://dx.doi.org/10.3390/life13020464
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