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The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool

The emergency department (ED) is the initial point of contact between hospital staff and patients potentially infected with SARS-CoV-2, thus, prevention of inadvertent exposure to other patients is a top priority. We aimed to assess whether the introduction of antigen-detecting rapid diagnostic test...

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Autores principales: Meltzer, Lilac, Amit, Sharon, Gilboa, Mayan, Tal, Ilana, Mechnik, Bella, Irony, Avi, Engelrad, Hindi, Epstein, Avi, Frenkel-Nir, Yael, Levy, Yuval, Kreiss, Yitshak, Regev-Yochay, Gili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961521/
https://www.ncbi.nlm.nih.gov/pubmed/36838249
http://dx.doi.org/10.3390/microorganisms11020284
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author Meltzer, Lilac
Amit, Sharon
Gilboa, Mayan
Tal, Ilana
Mechnik, Bella
Irony, Avi
Engelrad, Hindi
Epstein, Avi
Frenkel-Nir, Yael
Levy, Yuval
Kreiss, Yitshak
Regev-Yochay, Gili
author_facet Meltzer, Lilac
Amit, Sharon
Gilboa, Mayan
Tal, Ilana
Mechnik, Bella
Irony, Avi
Engelrad, Hindi
Epstein, Avi
Frenkel-Nir, Yael
Levy, Yuval
Kreiss, Yitshak
Regev-Yochay, Gili
author_sort Meltzer, Lilac
collection PubMed
description The emergency department (ED) is the initial point of contact between hospital staff and patients potentially infected with SARS-CoV-2, thus, prevention of inadvertent exposure to other patients is a top priority. We aimed to assess whether the introduction of antigen-detecting rapid diagnostic tests (Ag-RDTs) to the ED affected the likelihood of unwanted SARS-CoV-2 exposures. In this retrospective single-center study, we compared the rate of unwarranted exposure of uninfected adult ED patients to SARS-CoV-2 during two separate research periods; one before Ag-RDTs were introduced, and one with Ag-RDT used as a decision-support tool. The introduction of Ag-RDTs to the ED significantly decreased the relative risk of SARS-CoV-2-negative patients being incorrectly assigned to the COVID-19 designated site (“red ED”), by 97%. There was no increase in the risk of SARS-CoV-2-positive patients incorrectly assigned to the COVID-19-free site (“green ED”). In addition, duration of ED admission was reduced in both the red and the green ED. Therefore, implementing the Ag-RDT-based triage protocol proved beneficial in preventing potential COVID-19 nosocomial transmission.
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spelling pubmed-99615212023-02-26 The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool Meltzer, Lilac Amit, Sharon Gilboa, Mayan Tal, Ilana Mechnik, Bella Irony, Avi Engelrad, Hindi Epstein, Avi Frenkel-Nir, Yael Levy, Yuval Kreiss, Yitshak Regev-Yochay, Gili Microorganisms Article The emergency department (ED) is the initial point of contact between hospital staff and patients potentially infected with SARS-CoV-2, thus, prevention of inadvertent exposure to other patients is a top priority. We aimed to assess whether the introduction of antigen-detecting rapid diagnostic tests (Ag-RDTs) to the ED affected the likelihood of unwanted SARS-CoV-2 exposures. In this retrospective single-center study, we compared the rate of unwarranted exposure of uninfected adult ED patients to SARS-CoV-2 during two separate research periods; one before Ag-RDTs were introduced, and one with Ag-RDT used as a decision-support tool. The introduction of Ag-RDTs to the ED significantly decreased the relative risk of SARS-CoV-2-negative patients being incorrectly assigned to the COVID-19 designated site (“red ED”), by 97%. There was no increase in the risk of SARS-CoV-2-positive patients incorrectly assigned to the COVID-19-free site (“green ED”). In addition, duration of ED admission was reduced in both the red and the green ED. Therefore, implementing the Ag-RDT-based triage protocol proved beneficial in preventing potential COVID-19 nosocomial transmission. MDPI 2023-01-21 /pmc/articles/PMC9961521/ /pubmed/36838249 http://dx.doi.org/10.3390/microorganisms11020284 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Meltzer, Lilac
Amit, Sharon
Gilboa, Mayan
Tal, Ilana
Mechnik, Bella
Irony, Avi
Engelrad, Hindi
Epstein, Avi
Frenkel-Nir, Yael
Levy, Yuval
Kreiss, Yitshak
Regev-Yochay, Gili
The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool
title The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool
title_full The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool
title_fullStr The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool
title_full_unstemmed The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool
title_short The Use of Rapid COVID-19 Antigen Test in the Emergency Department as a Decision-Support Tool
title_sort use of rapid covid-19 antigen test in the emergency department as a decision-support tool
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961521/
https://www.ncbi.nlm.nih.gov/pubmed/36838249
http://dx.doi.org/10.3390/microorganisms11020284
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