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EGFR and p38(MAPK) Contribute to the Apoptotic Effect of the Recombinant Lectin from Tepary Bean (Phaseolus acutifolius) in Colon Cancer Cells

Previous works showed that a Tepary bean lectin fraction (TBLF) induced apoptosis on colon cancer cells and inhibited early colonic tumorigenesis. One Tepary bean (TB) lectin was expressed in Pichia pastoris (rTBL-1), exhibiting similarities to one native lectin, where its molecular structure and in...

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Detalles Bibliográficos
Autores principales: Dena-Beltrán, José Luis, Nava-Domínguez, Porfirio, Palmerín-Carreño, Dulce, Martínez-Alarcón, Dania, Moreno-Celis, Ulisses, Valle-Pacheco, Magali, Castro-Guillén, José Luis, Blanco-Labra, Alejandro, García-Gasca, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961623/
https://www.ncbi.nlm.nih.gov/pubmed/37259433
http://dx.doi.org/10.3390/ph16020290