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Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication

Here we describe the case of a potentially lethal caffeine intoxication after the reported ingestion of 10 g of caffeine. Due to hemodynamic instability with tachycardia and hypertension with an insufficient effect of continuous labetalol infusion, the patient was started on continuous veno-venous h...

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Autores principales: Reimerink, Elles J., Huntjens, Daan W., Pelkmans, Lindsey G., Geerts, Jan-Willem H. J., Franssen, Eric J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961704/
https://www.ncbi.nlm.nih.gov/pubmed/36851070
http://dx.doi.org/10.3390/toxics11020196
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author Reimerink, Elles J.
Huntjens, Daan W.
Pelkmans, Lindsey G.
Geerts, Jan-Willem H. J.
Franssen, Eric J. F.
author_facet Reimerink, Elles J.
Huntjens, Daan W.
Pelkmans, Lindsey G.
Geerts, Jan-Willem H. J.
Franssen, Eric J. F.
author_sort Reimerink, Elles J.
collection PubMed
description Here we describe the case of a potentially lethal caffeine intoxication after the reported ingestion of 10 g of caffeine. Due to hemodynamic instability with tachycardia and hypertension with an insufficient effect of continuous labetalol infusion, the patient was started on continuous veno-venous haemodialysis (CVVHD). After successful treatment for 15 h, CVVHD could be discontinued, and the patient was discharged home the next day. This case report is the first to report the use of CVVHD as a haemodialysis modality in the case of caffeine intoxication and illustrate the effect on caffeine clearance. We stress the importance of an early recognition of caffeine intoxication, so that haemodialysis can be considered in the case of a potentially lethal intoxication.
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spelling pubmed-99617042023-02-26 Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication Reimerink, Elles J. Huntjens, Daan W. Pelkmans, Lindsey G. Geerts, Jan-Willem H. J. Franssen, Eric J. F. Toxics Case Report Here we describe the case of a potentially lethal caffeine intoxication after the reported ingestion of 10 g of caffeine. Due to hemodynamic instability with tachycardia and hypertension with an insufficient effect of continuous labetalol infusion, the patient was started on continuous veno-venous haemodialysis (CVVHD). After successful treatment for 15 h, CVVHD could be discontinued, and the patient was discharged home the next day. This case report is the first to report the use of CVVHD as a haemodialysis modality in the case of caffeine intoxication and illustrate the effect on caffeine clearance. We stress the importance of an early recognition of caffeine intoxication, so that haemodialysis can be considered in the case of a potentially lethal intoxication. MDPI 2023-02-20 /pmc/articles/PMC9961704/ /pubmed/36851070 http://dx.doi.org/10.3390/toxics11020196 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Reimerink, Elles J.
Huntjens, Daan W.
Pelkmans, Lindsey G.
Geerts, Jan-Willem H. J.
Franssen, Eric J. F.
Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication
title Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication
title_full Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication
title_fullStr Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication
title_full_unstemmed Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication
title_short Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication
title_sort successful use of continuous veno-venous haemodialysis in a case of potential lethal caffeine intoxication
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961704/
https://www.ncbi.nlm.nih.gov/pubmed/36851070
http://dx.doi.org/10.3390/toxics11020196
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