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Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia

Background: Accurate mortality data associated with infectious diseases such as coronavirus disease 2019 (COVID-19) are often unavailable in countries with fragile health systems such as Somalia. We compared officially reported COVID-19 deaths in Somalia with COVID-19 deaths estimated using verbal a...

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Autores principales: Afrah, Tahlil Abdi, Nyagah, Lilly M., Ali, Asma Swaleh, Karanja, Mary, Nor, Hassan W., Abera, Solomon, Mohamed, Ali Sh, Guled, Mohamed Ahmed Yusuf, Biday, Mohamed Mohamud Hassan, Obtel, Majdouline, Malik, Sk Md Mamunur Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961735/
https://www.ncbi.nlm.nih.gov/pubmed/36839600
http://dx.doi.org/10.3390/pathogens12020328
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author Afrah, Tahlil Abdi
Nyagah, Lilly M.
Ali, Asma Swaleh
Karanja, Mary
Nor, Hassan W.
Abera, Solomon
Mohamed, Ali Sh
Guled, Mohamed Ahmed Yusuf
Biday, Mohamed Mohamud Hassan
Obtel, Majdouline
Malik, Sk Md Mamunur Rahman
author_facet Afrah, Tahlil Abdi
Nyagah, Lilly M.
Ali, Asma Swaleh
Karanja, Mary
Nor, Hassan W.
Abera, Solomon
Mohamed, Ali Sh
Guled, Mohamed Ahmed Yusuf
Biday, Mohamed Mohamud Hassan
Obtel, Majdouline
Malik, Sk Md Mamunur Rahman
author_sort Afrah, Tahlil Abdi
collection PubMed
description Background: Accurate mortality data associated with infectious diseases such as coronavirus disease 2019 (COVID-19) are often unavailable in countries with fragile health systems such as Somalia. We compared officially reported COVID-19 deaths in Somalia with COVID-19 deaths estimated using verbal autopsy. Methods: We interviewed relatives of deceased persons to collect information on symptoms, cause, and place of death. We compared these data with officially reported data and estimated the positive and negative predictive values of verbal autopsy. Results: We identified 530 deaths during March–October 2020. We classified 176 (33.2%) as probable COVID-19 deaths. Most deaths (78.5%; 416/530) occurred at home and 144 (34.6%) of these were attributed to COVID-19. The positive predictive value of verbal autopsy was lower for home deaths (22.3%; 95% CI: 15.7–30.1%) than for hospital deaths (32.3%; 95% CI: 16.7–51.4%). The negative predictive value was higher: 97.8% (95% CI: 95.0–99.3%) for home deaths and 98.4% (95% CI: 91.5–100%) for hospital deaths. Conclusions Verbal autopsy has acceptable predictive value to estimate COVID-19 deaths where disease prevalence is high and can provide data on the COVID-19 burden in countries with low testing and weak mortality surveillance where home deaths may be missed.
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spelling pubmed-99617352023-02-26 Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia Afrah, Tahlil Abdi Nyagah, Lilly M. Ali, Asma Swaleh Karanja, Mary Nor, Hassan W. Abera, Solomon Mohamed, Ali Sh Guled, Mohamed Ahmed Yusuf Biday, Mohamed Mohamud Hassan Obtel, Majdouline Malik, Sk Md Mamunur Rahman Pathogens Article Background: Accurate mortality data associated with infectious diseases such as coronavirus disease 2019 (COVID-19) are often unavailable in countries with fragile health systems such as Somalia. We compared officially reported COVID-19 deaths in Somalia with COVID-19 deaths estimated using verbal autopsy. Methods: We interviewed relatives of deceased persons to collect information on symptoms, cause, and place of death. We compared these data with officially reported data and estimated the positive and negative predictive values of verbal autopsy. Results: We identified 530 deaths during March–October 2020. We classified 176 (33.2%) as probable COVID-19 deaths. Most deaths (78.5%; 416/530) occurred at home and 144 (34.6%) of these were attributed to COVID-19. The positive predictive value of verbal autopsy was lower for home deaths (22.3%; 95% CI: 15.7–30.1%) than for hospital deaths (32.3%; 95% CI: 16.7–51.4%). The negative predictive value was higher: 97.8% (95% CI: 95.0–99.3%) for home deaths and 98.4% (95% CI: 91.5–100%) for hospital deaths. Conclusions Verbal autopsy has acceptable predictive value to estimate COVID-19 deaths where disease prevalence is high and can provide data on the COVID-19 burden in countries with low testing and weak mortality surveillance where home deaths may be missed. MDPI 2023-02-15 /pmc/articles/PMC9961735/ /pubmed/36839600 http://dx.doi.org/10.3390/pathogens12020328 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Afrah, Tahlil Abdi
Nyagah, Lilly M.
Ali, Asma Swaleh
Karanja, Mary
Nor, Hassan W.
Abera, Solomon
Mohamed, Ali Sh
Guled, Mohamed Ahmed Yusuf
Biday, Mohamed Mohamud Hassan
Obtel, Majdouline
Malik, Sk Md Mamunur Rahman
Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia
title Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia
title_full Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia
title_fullStr Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia
title_full_unstemmed Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia
title_short Value of Verbal Autopsy in a Fragile Setting: Reported versus Estimated Community Deaths Associated with COVID-19, Banadir, Somalia
title_sort value of verbal autopsy in a fragile setting: reported versus estimated community deaths associated with covid-19, banadir, somalia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961735/
https://www.ncbi.nlm.nih.gov/pubmed/36839600
http://dx.doi.org/10.3390/pathogens12020328
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